摘要
目的探讨孟鲁司特佐治婴幼儿毛细支气管炎的疗效。方法将80例毛细支气管炎患儿随机分为两组,两组均采用综合治疗,观察组加用孟鲁司特口服,对治疗前后喘憋缓解、咳嗽消失、哮鸣音消失、湿啰音消失时间及治愈率进行比较。结果观察组喘憋缓解时间为(2.65±1.13)d、咳嗽消失时间为(5.72±2.51)d、哮鸣音消失时间为(4.86±1.53)d、湿啰音消失时间为(6.57±1.92)d,以上方面均优于对照组,差异均有统计学意义(t分别=3.53、3.79、6.92、2.46,P均<0.05),治愈率为92.86%高于对照组71.05%,差异亦有统计学意义(χ2=5.15,P<0.05)。结论孟鲁司特对婴幼儿毛细支气管炎有一定疗效,且方便、安全,可作为佐治毛细支气管炎的药物。
Objective To investigate the clinical effect of montelukast on the treatment of infant bronchiolitis. Methods Eighty infants suffered from bronchiolitis were randomly divided into two group： the treatment group （montelukast group, 42 cases） and the control group （routine treatment group, 38 cases）.The control group were treated with synthetic therapy and the treatment group were assist-treated with montelukast based on the same synthetic therapy . The clinical effect and recovery rate were evaluated in both groups. Results Compared with the control group, the study group showed a rapider improvement in respiratory symptoms： the dyspnea relieved after （ 2.65 ± 1.13 ） days, the cough disappeared after （5.72±2.51 ） days, the wheezing disappeared after （4.86± 1.53 ） days and the moist rale disappeared after （6.57±1.92）days. The differences of symptom-free days between the two groups were significant （t=3.53,3.79,6.92, 2.46, P〈0.05）. The study group had a higher recovery rate 92.86% than the control group 71.05%. There was statistical difference between these two groups（x2=5.15, P〈0.05）. Conclusions The clinical symptoms of bronchiolitis can be controlled with montelukast, which is convenient and safe. It can be one of the assist-treated drugs in the infant with bronchiolitis.
出处
《全科医学临床与教育》
2010年第2期159-161,共3页
Clinical Education of General Practice
