摘要
该文研究一个描述药物作用下肿瘤生长的数学模型,这个肿瘤模型是对Jackson模型的一个改进,其数学形式是由一个二阶非线性抛物型方程与两个一阶非线性偏微分方程组耦合而成的自由边界问题.通过运用抛物型方程的L^P理论与一阶偏微分方程的特征方法,并利用Banach不动点定理,证明了该问题存在唯一的整体经典解.
In this paper a mathematical model for the effect of drugs in the growth of tumors is studied.This model is a modification of the Jackson model by dividing tumor cells into three classes：proliferating cells,dormant cells and dead cells.The model is a free boundary problem of a system of partial differential equations comprising a second-order nonlinear parabolic equation and two first-order nonlinear partial differential equations.By applying the L^p theory of parabolic equations,the characteristic method for first-order partial differential equations, and the Banach fixed point theorem,existence and uniqueness of the global classic solution are established.
出处
《数学物理学报（A辑）》
CSCD
北大核心
2010年第2期305-319,共15页
Acta Mathematica Scientia
基金
国家自然科学基金(10771223)资助
关键词
肿瘤生长
自由边界问题
整体解
Tumor growth
Free boundary problem
Global solution
作者简介
E-mail： wjdmath@163.com;
cuisb3@yahoo.com.cn
