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山西省长治东部农村地区糖尿病视网膜病变的流行病研究 被引量:20

Eoidemiologic studay on the prevalence rate and risk factors of diabetic retinopathy in eastern countryside of Changzhi
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摘要 目的 调查山西省长治东部农村糖尿病患者糖尿病视网膜病变(DR)的患病情况及影响因素.方法 以当地农村合作医疗档案为基础,对当地15岁以上居民63 409人进行糖尿病普查,标准参照1997年WHO通过的糖尿病诊断标准.对检出的2632例糖尿病患者通过询问和检查获得病史、糖化血红蛋白(HbA_(1c))、空腹血糖、视力、眼病、眼压等资料,采用免散瞳眼底照相进行DR诊断,诊断标准参照中华医学会眼科学分会眼底病学组1985年制定的DR分期标准.单眼或双眼DR均人选为DR患者.运用SPSS 13.0软件进行统计学分析.结果 实际受检57 500人,受检率90.68%,检出2632例糖尿病患者,DR患者986例,患病率37.46%.糖尿病病程与DR的患病率有显著相关(r=0.210,P〈0.001).糖尿病病程以及同时患有高血压病变是依次影响DR病情发展到增生型的因素.非DR患者与DR患者视力损伤差异有统计学意义(P〈0.01).HbA_(1c)水平与DR发生率显著正相关(t=9.25,P〈0.01).结论 山西省长治东部农村糖尿病患者中DR患病率高 糖尿病病程及同时患有高血压病变是依次影响DR病情发展到增生型的因素 HbA_(1c)水平可作为监测糖尿病患者DR发生、发展的重要指标. Objective To estimate the prevalence rate and risk factors of diabetic retinopathy (DR) in rural residents in Changzhi. Methods With the help of an established resident health data, a epidemiology study was performed on 63 409 residents (≥15 years old) in the rural area of Changzhi while the standard of diagnosis of diabetes was in accordance with the standard made by WHO in 1997. Diabetes was diagnosed in 2632 residents, and these patients underwent the investigation and examination including the disease history, glycosylated hemoglobin (HbAlc), fasting blood glucose, visual acuity, ocular diseases and intraocular pressure. The standard of DR was drawn according to the diagnosis standard made by Chinese Ocular Fundus Diseases Society, Chinese Ophthalmological Society, Chinese Medical Association in 1985. The data was statistically analyzed by SPSS 13.0 software. Results A total of 57 500 residents underwent the examination with the participating rate of 90.68% 2632(4. 58%) were diagnosed as with diabetes, in whom 986 were with DR (with DR prevalence of 37.46%). The duration of diabetes was the independent risk factor of DR (r=0. 210,P〈0. 001). The duration of diabetes and combined with hypertension were the influence factors of the development of DR. The visual acuity in residents with or without DR differed significantly(P〈0.01). The level of HbA1c was positively related to DR. Conclusions The incidence of DR is high in residents with diabetes in eastern countryside area of Changzhi. The duration of diabetes and combined with hypertension were the influence factors of the development of DR. The level of HbAlc may be the important indicator which can monitor the occurrence and development of DR in patients with diabetes.
出处 《中华眼底病杂志》 CAS CSCD 北大核心 2010年第2期109-112,共4页 Chinese Journal of Ocular Fundus Diseases
关键词 糖尿病视网膜病变/流行病学 糖尿病视网膜病变/诊断 流行病学方法 Diabetic retinopathy/epidemiology Diabetic retinopathy/diagnosis Epidemiologic methods
作者简介 王红波,Email:wanghongb0986@163.com 通信作者
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参考文献20

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