摘要
目的探讨前白蛋白（PA）在手足口病病情监测及预后中的应用价值。方法检测390例患儿治疗过程中及治疗前后血清PA水平，比较其在治疗过程中的变化，并观察病例预后情况。结果病情加重组PA在第1—7天持续降低，第7天与第1和3天比较差异显著（t值分别为14．073和11．104，均P〈0．01）。PA水平与SPAS11评分间呈明显负相关（r=-0.564。P〈0．01）。结论PA水平在手足口患儿经有效治疗后可发生显著变化，PA检测对手足口病预后观察具有重要临床意义。
Objective To explore the curative effect of prealbumin （PA） in the hand-foot-and-mouth dis- ease and analysis its value in monitoring and prognosing this disease. Method Detect levels of serum PA of 390 ca- ses of children Lefore, after and during the treatment and compare the changes during the treatment. Then observe the prognosis. Results There are significant difference of PV levels between cases of different prognosis （ P 〈 0.05 ）. Conclusion The PV levels of children of hand-foot-and-mouth disease will change significantly after effective treat- ment. There are clinical significance in observing and prognosing tile hand-foot-and-mouth disease by detecting the se- rum PV levels.
出处
《中国基层医药》
CAS
2010年第4期437-438,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
手足口病
前白蛋白
Hand,foot and mouth disease
Prealbumin
