摘要
目的研究儿童过敏性紫癜(HSP)的临床特征。方法对124例HSP患儿的临床资料进行回顾性分析。结果54.84%(68/124)的患儿起病前有明确的上呼吸道感染史。紫癜性肾炎组中63.83%(30/47)的患儿出现皮肤紫癜反复,非紫癜性肾炎组中28.57%(22/77)的患儿出现皮肤紫癜反复,差异显著(P<0.05)。同时具有皮肤紫癜、消化道症状及关节症状的患儿肾脏受累发生率高于单纯皮肤紫癜患儿(P<0.05)。67.35%的患儿血清IgA升高,39.39%的患儿C反应蛋白水平升高。结论上呼吸道感染为主要发病诱因,皮肤紫癜反复出现的HSP患儿及同时具有皮肤紫癜、消化道症状和关节症状的HSP患儿肾脏受累几率明显升高。
Objective To study the clinical characteristics of Henoch-Schnlein purpura（HSP）in children. Methods We retrospectively analyzed the clinical data of 124 children with HSP. Results Among these 124 children,54.84% of the children presented upper respiratory tract infection before the onset of HSP. The purpura recurred in 30 of 47 children with Henoch-Schnlein purpura nephritis and in 22 of 77 children without Henoch-Schnlein purpura nephritis,respectively （P 〈 0.05）. The incidence of Henoch-Schnlein purpura nephritis was significantly higher in children who had purpura,gastrointestinal symptoms,and joint symptoms simultaneously than in those only with purpura （P 〈 0.05）. The elevated levels of IgA and C reactive protein were found in 67.35% and 39.39% of the children,respectively. Conclusion The most important predisposing factor of HSP is upper respiratory tract infection. The children with recurrence of purpura or those who have purpura,gastrointestinal symptoms,and joint symptoms simultaneously are more likely to present renal damage.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2010年第1期58-60,共3页
Journal of China Medical University
关键词
过敏性紫癜
儿童
Henoeh-Sehonlein purpura
children
作者简介
张悦（1980-），女，主治医师，硕士．
通讯作者：韩秀萍，E-mail：hanxp@sj-hospital．org
