罗哌卡因复合舒芬太尼用于臂丛神经阻滞术后镇痛的效果评价被引量：12

A Clinical Effect of Continuous Interscalene Nerve Block with Ropivacaine Adding Sufentanil for Postoperative Analgesia

在线阅读下载PDF

导出

摘要目的:评价舒芬太尼复合罗哌卡因用于臂丛神经阻滞术后镇痛的效果。方法:选择60例在臂丛神经阻滞复合全麻下行择期肱骨近端骨折切开复位内固定术并行连续臂丛神经阻滞术后镇痛的患者,随机分为两组:观察组(n=30)用药为0.2μg.mL-1舒芬太尼和0.2%罗哌卡因,对照组(n=30)为0.2%罗哌卡因。分别记录两组用药量、静息和运动VAS评分、PONV及患者满意度。结果:两组间静息和运动VAS评分、PONV及患者满意度差异均无统计学意义。结论:复合0.2μg.mL-1的舒芬太尼不能增强0.2%罗哌卡因连续臂丛神经阻滞术后镇痛的镇痛效果。 Objective：To evaluate the clinical effect of adding 0.2 μg · mL^-1 sufentanil to 0.2% ropivacaine during continuous peripheral nerve block. Methods： Sixty ASA Ⅰ-Ⅱ patients undergoing elective proximal humerus surgery, who needed continuous intersealene nerve block for postoperative analgesia, were randomly allocated into two groups in a double-blind fashion. Group one were given 400 mL of 0.2% ropivacaine alone （n = 30） ; while Group two were given 0.2% ropivaeaine plus 0.2 μg · mL^-1 sufentanil （n = 30）. The VAS score and the incidence of PONV, as well as anesthesia parameters were recorded. Results： No statistical differences was found on the VAS score between the two groups. No differences regarding the incidence of oversedation, PONV and itching were observed between two groups. Conclusion： Adding sufentanil 0.2 μg · mL^-1 to 0.2% ropivacaine solution did not provide significant advantages of continuous interscalene nerve block for postoperative analgesia in patients undergoing elective proximal humerus surgery.

作者许莉张昊华王怀江林惠华李世忠

机构地区北京积水潭医院麻醉科北京积水潭医院矫形骨科

出处《中国临床医学》 2009年第6期946-948,共3页 Chinese Journal of Clinical Medicine

关键词罗哌卡因舒芬太尼术后镇痛臂丛神经阻滞 Ropivacaine Sufentanil Postoperative analgesia Interscalene nerve block

分类号 R614.4 [医药卫生—麻醉学]

作者简介通讯作者林惠华，E—mail：6huihua@vip．sina．com.

引文网络
相关文献

参考文献6

1Fields HI., Emcen PC. Leigh BK. et al. Multiple opiate receptor sites on primary afferent fibres[J]. Nature, 1980,284:351-353.
2沈霞,葛宁花,缪长虹,薛张纲.等效剂量舒芬太尼或芬太尼术后硬膜外或静脉患者自控镇痛效应的观察[J].中国临床医学,2005,12(5):913-915. 被引量：9
3Nishikawa K, Kanaya N. Nakayama M,et al. Fentanyl improves analgesia but prolongs the onset of axillary brachial plexus block by peripheral mechanism[J]. Anesth Analg, 2000,91 (2):384-387.
4Bazin JE, Massoni C, Bruelle P,et al. The addition of opioids to local anaesthetics in brachial plexus block: the comparative effects of morphine, buprenorphine and sufentanil[J].Anaesthesia. 1997,52(9):858- 862.
5Bouaziz H, Kinirons BP, Macalou D, et al. Sufentanil does not prolong the duration of analgesia in a meplvaeaine brachial plexus block: a dose response study[J]. Anesth Analg, 2000,90(2): 383-387.
6Borghi B, Facchini F, Agnoletti V, et al. Pain relief and motor function during continuous interscalene analgesia after open shoulder surgery: a prospective, randomized, double blind comparison between levobupivacaine 0.25 %, and ropivacaine 0.25% or 0.4%[J]. Eur J Anaesthesiol JT, 2006,23(12) :1005- 1009.

二级参考文献7

1Clotz MA, Nahata MC. Clinical uses of fentanil[J], sufentanil and alfentanil. Clin Pharm, 1991,10:581.
2Ledin Eriksson S, Gentele C, Olofsson CH. PCEA compared to continuous epidural infusion in an ultra-low-dose regimen for labor pain relief: a randomized study[J]. Acta Anaesthesiol Scand, 2003,47(9):1085-1090.
3Joris JL, Jacob EA, Sessler DI,et al. Spinal mechanisms contribute to analgesia produced by epidural sufentanil combined with bupivacaine for postoperative analgesia[J]. Anesth Analg, 2003, 97(5):1446-1451.
4Bernard JM, Le Roux D, Barthe A, et al. The dose-range effects of sufentanil added to 0. 125% bupivacaine on the quality of patient-controlled epidural analgesia during labor[J]. Anesth Analg, 2001, 92(1):184-188.
5Kampe S, Randebrock G, Kiencke P, et al. Comparison of continuous epidural infusion of ropivacaine and sufentanil with intravenous patientcontrolled analgesia after total hip replacement[J]. Anaesthesia, 2001,56(12) :1189-1193.
6Lorenzini C, Moreira LB, Ferreira MB, et al. Efficacy of ropivacaine compared with ropivacaine plus sufentanil for postoperative analgesia after major knee surgery[J]. Anaesthesia, 2002, 57(5):424-428.
7Vijavan R, Delilkan AE. First year,s experience with an acute pain service University Hospital Kual Lumpur[J]. Med J Malaysia, 1994, 49:385-390.