摘要
目的建立兔急性肾动脉狭窄模型,探讨多普勒超声对不同程度肾动脉狭窄的诊断价值。方法对10只兔递进钳夹左肾动脉主干,钳夹程度分4级:0级:正常;Ⅰ级:钳夹动脉主干1/3;Ⅱ级:钳夹动脉主干2/3;Ⅲ级:完全钳夹。对各钳夹级别肾脏进行彩色多普勒超声检查,测量肾动脉狭窄段和叶间动脉血流动力学参数。结果①钳夹肾动脉1/3时,肾动脉狭窄段血流频谱呈高速湍流频谱,叶间动脉频谱形态改变不明显。钳夹肾动脉2/3时,肾动脉狭窄段血流频谱呈毛刺状,流速进一步加快,叶间动脉频谱形态呈实心圆钝样。肾动脉完全闭塞时,肾动脉及肾内动脉无血流信号,测不到血流频谱。②肾动脉峰值流速Ⅰ级组和Ⅱ级组均显著高于0级组(P<0.05),Ⅱ级组高于Ⅰ级组(P<0.05)。叶间动脉峰值流速、舒张末期流速、收缩期加速度、阻力指数,Ⅰ级组高于Ⅱ级组(P<0.05),收缩期加速时间Ⅱ级组比0、Ⅰ级组延长(P<0.05)。结论多普勒超声综合观察肾动脉局部和肾内动脉血流动力学指标能够提高肾动脉狭窄的诊断价值。
Objective Rabbit model of acute renal artery stenosis was made in order to evaluate the diagnostic value of varying degrees of renal artery stenosis （RAS） by Doppler ultrasound. Methods The left renal arteries of 10 rabbits were progressively stenosed in various degree ： 0 degree- the normal control,Ⅰ degree-to stenose 1/3 of the artery, Ⅱ degree-to stenose 2/3 of the artery, m degree-to obstruct the artery totally. The blood flow parameters of the stenotic renal artery and interlobar arteries of different rabbits were measured by using the Doppler ultrasound. Results （1） When renal arteries were stenosed 1/3, the spectrum of the segment showed high speed, but the spectrum of the interlobar arteries did not change significantly. When renal arteries were stenosed 2/3, the spectrum of the segment showed higher speed, and the spectrum of interlobar arteries was round and blunt. When renal arteries were obstructed, there were no signal of blood. （2） In Ⅰ degree and Ⅱ degree group, VP was higher than 0 degree group, VP in R degree group was higher than that of Ⅰ degree group （P〈0.05）. VP,Vm ,ACC ,RI of interlobar arteries in degree group was lower than in 0 degree and Ⅰ degree group, and AT in Ⅱ degree group was longer than that of in 0 degree and Ⅰ degree group （P〈0.05）. Conclusion To evaluate the indexes representing hemodynamic of local renal arteries and renal interlobar arteries is helpful to diagnosis RAS.
出处
《实用医技杂志》
2010年第1期25-27,共3页
Journal of Practical Medical Techniques
关键词
肾动脉梗阻
检查
多普勒
彩色
血流动力学
Renal artery obstruction
Uhrasonography, Doppler, color
Hemodynamies
