摘要
探讨血浆内皮素（ＥＴ）、降钙素基因相关肽（ＣＧＲＰ）和神经肽（ＮＰＹ）与老年人动脉硬化之间的关系，提高动脉硬化的预防和治疗效果。方法用放射免疫法对３０例５５岁以上老人进行血浆ＥＴ、ＣＧＲＰ和ＮＰＹ的测定，并与５０例健康青年人做对照。结果老年组ＥＴ升高，ＣＧＲＰ、ＮＰＹ降低（Ｐ＜０．０５～０．０１）。结论ＥＴ升高，ＣＧＲＰ、ＮＰＹ降低表明老年人心血管分泌及调节功能失调，提示该改变可能与老年人心脑血管疾病的发生有关。
Objectives To study on the retation between plasma endothelin (ET),neuropeptide Y(NPY) and calcitonin gene related Peptide(CGRP) and atherosclerosis in elderly to look for new ways of Prevention and treatment.Methods To determinate the levels of ET,NPY and CGRP in 30 elderly in radioimmunoassay and to control them with 50 health youth.Results ET level of elderly group increased,levels of CGRP and NPY decreased,(P<0.05～0.01).Conclusion The changes demonstrated that the cardiovascular secretory and regulatory function were disorder in the elderly.They suggest that the changes may be related to cardiovasculer and brain diseases of the elderly.
出处
《宁夏医学杂志》
CAS
1998年第5期294-295,共2页
Ningxia Medical Journal
