摘要
研制出一种新型超低温冷冻医疗系统,利用预冷后的氮气在冷刀头的J-T效应产生所需低温。经实验,并考虑经济性因素等,确定氮气输入压力为8.5MPa,氮气预冷温度为-125℃。20℃纯水中的性能实验表明,10分钟内可形成最大直径约4cm、长度为5.8cm的冰球,优于相同规格的氩氦冷刀;在猪肝中,前10分钟可形成直径3.7cm的冰球,冰球生长速度较快;猪活体实验中,4天后冷冻区肝细胞完全死亡,15天后,交界处形成结缔组织增生带。
A new type of ultra-cryoablation system was developed to obtain the needed low-temperature on the tip ofa cryoprobe by J-T effect using pre-cooling Nitrogen. The input-pressure and the pre-cooling temperature of nitrogen were determined to be 8.5MPa and -125℃, respectively, by the experiment and in consideration of the economic factor. The performance test shows that the cryoprobe could generate the ice ball with a diameter of up to 4cm and the length of 5.8cm in 20℃ water for ten minutes, better than an argonhelium cryoprobe. The ice ball with a diameter of 3.7cm were generated in a pig liver in the first ten minutes and it grew fast. In the experiment on a living pig, the liver cell in the frozen section was completely dead after four days and the connective tissue occurred at the edge of the frozen section after fifteen days.
出处
《制冷学报》
CAS
CSCD
北大核心
2009年第6期57-60,共4页
Journal of Refrigeration
基金
上海市研究生创新基金项目资助(JWCXSL0801)~~
作者简介
作者联系方式：E—mail：kevin_212@usst．edu．cn
