摘要
目的:通过临床病例,观察凉血化瘀中药治疗特发性脉络膜新生血管(idiopathic choroidal neovascularization,ICNV)的疗效。方法:对46例46眼确诊的ICNV病变患者服凉血化瘀中药治疗,服中药3mo,总观察时间9mo。观察比较治疗前后最佳矫正视力(best corrected visual acuity,BCVA)、荧光眼底血管造影(fundus fluorescein angiography,FFA)和光学相干断层扫描(optic coherent tomography,OCT)图像。结果:末次随访时,中药治疗46眼中,视力平均提高0.21,较治疗前有统计意义;FFA检查发现:显效(CNV闭合)34眼(73.9%),有效(CNV部分闭合)7眼(15.2%),进步(CNV小部分闭合)4眼(8.7%),无效(CNV扩大)0眼,较治疗前显著改善。OCT检查发现:CNV型别由治疗前活动期38眼(82.6%)、中间期8眼(17.4%),转变为有效(瘢痕期)38眼(82.6%),进步(中间期)6眼(13.1%),无效(活动期)2眼(4.4%),具有统计学意义。结论:中药凉血化瘀可以促进ICNV中CNV闭合。
AIM：To investigate the therapeutic effect of liang-xuehuayu decoction for the treatment of idiopathic choroidal neovascularization（ICNV）.·METHODS：The clinical data of 46 patients（46 eyes） with ICNV who had been followed up for 9 months after therapy of Chinese medicine for CNV were analyzed.The changes of the best corrected visual acuity（BCVA）,fundus fluorescein angiography（FFA） and optic coherent tomography（OCT） were observed and analyzed.·RESULTS：At the end of the follow-up period,the BCVA improved 0.21,the vision improved obviously（≥2 lines） in 25 eyes（54.3%）,kept stable（changed within 1line） in 16 eyes（34.8%）,and decreased（≥2 lines） in 5 eyes（10.9%）.The results of FFA showed completely closed CNV in 34 eyes（73.9%）,partly closed CNV in 7 eyes（15.2%）,unclosed CNV in 4 eyes（8.7%） and enlarged CNV in 0 eye.OCT showed scar stage in 38 eyes（82.6%）,middle stage in 6 eyes（13.1%） and active stage in 2 eyes（4.4%）.·CONCLUSION：Chinese medicine of liangxuehuayu is an effective treatment for most patients with CNV caused by ICNV and can promote the closure of CNV.
出处
《国际眼科杂志》
CAS
2009年第11期2195-2197,共3页
International Eye Science
关键词
中药
脉络膜新生血管
特发性脉络膜新生血管
凉血化瘀
traditional Chinese medicine choroidal neovascularization idiopathic choroidal neovasculariza-tion liangxuehuayu
作者简介
李学晶，女，博士，主治医师，研究方向：眼底病的中医药防治及机理研究。通讯作者：李学晶．zw71@yahoo．com.cn
