摘要
多甲氧基黄酮类化合物紫花牡荆素是中国传统中草药蔓荆子的主要活性成分之一,具有抗炎、抗肿瘤等功效。本文对紫花牡荆素的来源、构效关系、抗肿瘤作用及其作用机制等的研究进展进行总结,以期为紫花牡荆素抗肿瘤作用机制的深入研究和临床开发应用提供参考。
Casticin, a ploymethoxyflavanoid casticin, possesses anti-inflammatory and anti-tumor properties. It is one of the major active components from Chinese herbal simpleteaf shrub chastetree fruit. This review summarized the research progress in casticin, in which the source, the relation between structure and activity, the anti-tumor effects and the underlying mechanisms were included. The main purpose of this review is to provide information for the ani-tumor effect of casticin and the potential clinical application.
出处
《国际病理科学与临床杂志》
CAS
2009年第5期403-406,共4页
Journal of International Pathology and Clinical Medicine
基金
湖南省卫生厅科研基金(B2007-116)~~
关键词
紫花牡荆素
构效关系
抗肿瘤作用
作用机制
Casticin
structure-activity relationship
anti-tumor effects
mechanism of action
作者简介
刘飞，硕士，主要从事抗肿瘤药物筛选和药理学的研究。
通讯作者：曹建国，E-mail：caojiangu02005@yahoo．com．cn
