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RNA干扰PI3Kp850L表达对乳腺癌MCF-7细胞放射增敏作用体外研究

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摘要 磷脂酰肌醇3激酶(phosphatidylinositol 3 kinase,P13K)参与多种信号通路,调节细胞功能,其异常表达与肿瘤细胞放射抵抗有关。笔者通过RNA干扰(RNA interference,RNAi)技术敲低人乳腺癌细胞系MCF-7中P13Kp85的表达,探讨肿瘤细胞放射敏感性变化。
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2009年第5期360-361,共2页 Chinese Journal of Radiation Oncology
作者简介 通信作者:张春智,Email:zhchzh_6@hotmail.com
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