摘要
目的了解临床标本中嗜麦芽寡养单胞菌的耐药性,指导临床合理治疗嗜麦芽寡养单胞菌的感染。方法常规培养分离细菌,用美国DADE BEHRING MicroScan分析系统鉴定菌种,药敏试验采用K-B纸片扩散法,按美国NCCLS规定标准执行。结果82株嗜麦芽寡养单胞菌对嗜麦芽寡养单胞菌除对左氧氟沙星,头孢哌酮/舒巴坦及复方磺胺甲恶唑的耐药率均<14.3%外,对头孢吡肟的耐药率为45.2%,对其余8种抗菌药物的耐药率均≥78.6%。尤其对亚胺培南的耐药率为100%。结论左氧氟沙星、头孢哌酮/舒巴坦及复方磺胺甲恶唑对所研究的嗜麦芽寡养单胞菌有较高的抗菌活性,系嗜麦芽寡养单胞菌严重感染治疗最有效的抗菌药物。
Objective To understand the drug resistance rates of 82 Stenotrophomonas maltophilia isolated from clinical infectious specimen in order to help clinic to treat Stenotrophomonas maltophilia infections rationally. Methods Bacteria culture and isolation used routine method. All isolates were identi fied by DADE BEHRING MicroScan microbe auto-system instrument. The drug susceptibility test used the K-B paper disk diffusion in accordance with NCCLS standards. Results Among 12 antibiotics,the resistance rates to Levofloxacin, Cefoperazone-Sulbactam and trimethoprim-sulfamethoxazole were lower than 14.3% ,the resistance rates to Cefepime was 45.2% ,the resistance rates to other eight antibiotics were all higher than 78.6%. Stenotrophomonas maltophilia was highly resistant to imipenem. Conclusion Levofloxacin, Cefoperazone-Sulbactam and trimethoprim-sulfamethoxazole were the most active antibiotics a- gainst Stenotrophomonas mahophilia,and were the most ideal antimicrobial agents for serious Stenotrophomonas maltophilia.
出处
《医学综述》
2009年第17期2701-2702,共2页
Medical Recapitulate
关键词
嗜麦芽寡养单胞菌
医院感染
耐药性
Stenotrophomonas maltophilia
Nosocomial infection
Drug resistance
