摘要
不表达雌、孕激素受体以及人类表皮生长因子受体-2的三阴乳腺癌，由于无法从较成熟的内分泌与赫赛汀靶向治疗中受益，成为目前乳腺癌治疗中较为棘手的亚群。识别三阴乳腺癌特异性分子生物学标志、选择适合的治疗方案及靶向治疗是目前研究的热点。
Triple negative phenotype breast cancers are characterized by lack of expression of estrogen receptor, progesterone receptor and human epithelial grouth factor receptor 2. This subgroup of cancers is insensitive to most available hormonal and targeted therapeutic agents. Identification of more molecular predictive signatures will enable us to design optimal treatment regimens and targeted therapies.
出处
《国际肿瘤学杂志》
CAS
2009年第8期593-596,共4页
Journal of International Oncology
基金
基金项目：上海市科学技术委员会科研计划项目（06DZ19505）
关键词
乳腺肿瘤
靶向治疗
药物治疗
Breast neoplasms
Targeted therapy
Drug therapy
