摘要
目的观察遥测心电监护系统心率变异性(HRV)分析在不同心血管疾病中的变化,评价遥测监护系统HRV检测的临床应用价值。方法入选160例在我院诊治的患者,其中正常组40例,急性心肌梗死组40例,高血压病组40例,糖尿病组40例,使用装载心率变异性分析软件的心电监护仪,进行心率变异监测,应用时域法分析HRV各项指标(SDNN、RMSSD、PNN50),观察各组患者与正常组心率变异性各指标的差异,比较急性心肌梗死后不同时间心率变异性的变化,分析心率变异性与室性心律失常的关系。结果心肌梗死组及糖尿病组患者心率变异性各指标较正常组明显降低(p<0.05),高血压组HRV时域指标SDNN较正常对照组降低明显(p<0.05),而RMSSD、PNN50与正常对照组比较差异无统计学意义(p>0.05)。急性心肌梗死组中,发病初期及第2周后短程心率变异性较正常对照组均明显降低,发生严重室性心律失常患者较未发生者明显降低(p<0.05)。结论遥测监护系统心率变异性时域指标降低可敏感地反映自主神经受损程度,可用于心血管疾病的病情预测和疗效评价,并指导临床治疗。
Objective To investigate the difference of the heart rate variability （HRV） analyzed by telemetry cardiogram monitor in the patients with different cardiovascular diseases and evaluate its practical clinical value of the HRV. Methods The HRV indices of 160 cases were examined by the telemetry cardiogram monitor loaded with HRV analysis software, 40 normal cases, 40 acute myocardial infarction （AMI） cases, 40 hypertension cases and 40 diabetes cases by analyzing the indices （SDNN, RMSSD, PNN50） of HRV, the difference of the indices were explored between disease groups and the normal group. Results In AMI group and diabetes group, the indices of HRV were significantly lower than those in normal controls （p〈0.05）. In hypertension group, the SDNN was significantly lower than that in normal group （p〈0.05）, otherwise, there was no difference in the RMSSD and PNN50 between normal group and hypertension group. In AMI group, the HRV indices of initial stage and after 2 weeks, were significantly lower than those in normal controls. And the indices in patient with serious ventricular arrhythmia were much lower than those with no serious ventricular arrhythmia in AMI group. Conclusions The HRV analyzed by telemetry cardiogram monitor can reflect the damage level of the heart autonomic nerve sensitively. It can be applied to predict the risk level, curative effect of the cardiovascular disease and direct clinical treatment.
出处
《临床心电学杂志》
2009年第3期172-174,共3页
Journal of Clinical Electrocardiology
关键词
遥测心电监护系统
心率变异性
自主神经
心血管疾病
telemetry cardiogram monitor, heart rate variability
autonomic nerve
cardiovascular diseases
