摘要
目的探讨血清高敏C反应蛋白(hs-CRP)指标的变化与急性冠脉综合征(ACS)发病之间的关系,以期发现这种变化与急性冠脉综合征发病的预测意义。方法选取河南省人民医院心内科2007年9月—2007年12月入院诊断为冠心病且入院后行冠脉造影术的患者100例为研究对象,急性冠脉综合征组(ACS组)62例,稳定型心绞痛组(SAP组)38例;另选取健康体检者30名为对照组(NCHD组)。以双抗体夹心酶联免疫吸附法(ELISA)检测血清hs-CRP。结果ACS组患者血清hs-CRP水平明显高于健康对照组(P<0.01);ACS组与SAP组血清hs-CRP水平比较,差异亦有统计学意义(P<0.05)。结论hs-CRP可作为急性冠脉综合征发病及判断其严重程度的重要血清标志物。
Objective To study the serum high sensitive C - reactive protein (hs -CRP) in patients (pts) with acute coronary syndrome. Methods One hundred pts with CHD,were divided into acute coronary syndrome(ACS) group(n=62) ,stable angina pectoris (SAP) group(n = 38) ,and healthy controls(NCHD) group(n= 30). The levels of serum hs -CRP were measured with enzyme- linked immunosorbent assay. Results The level of serum hs - CRP was significantly higher in the AC.S group than that in NCHD group(P〈0.01). There was significantly difference in the level of serum hs - CRP between the ACS group and SAP group(P〈0.05). Conclusion Serum hs - CRP was one of the indexes for the inflammation of atheroselerosis, which was an important serum maker of the attack and serve degree of ACS.
出处
《中西医结合心脑血管病杂志》
2009年第7期766-767,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
国家重点基础研究发展规划基金项目973计划(No.2003CB517103)
关键词
高敏C反应蛋白
急性冠脉综合征
相关性
血清标志物
high sensitive C - reactive protein
acute coronary syndrome
correlation
serum maker
作者简介
陈召起(1976-),男.毕业于河南中医学院,主治医师,硕士研究生,现工作于河南省肿瘤医院(邮编:450003);