摘要
术后认知功能障碍(POCD)是老年人手术后的常见并发症。导致老年人日常行为能力下降,给家庭和社会带来沉重的负担。60岁以上的患者行非心脏大手术后1周POCD的发生率为25.8%,3个月时为9.9%。POCD的高危因素包括:高龄、术前认知功能受损以及酗酒等。POCD虽然有较多相关因素,但其发病原因及机制仍不清楚。本文就老年人非心脏大手术POCD的相关因素作一综述。
Postoperative cognitive dysfunction (POCD) has been reported after a variety of surgical procedures in the elderly. POCD is associated with a decline in performance of activities of daily living of elderly patients and can cause substantial damage to family and to social support systems. The incidence of POCD in the first week after major noncardiae surgery is 25.8% in patients older than 60. Cognitive dysfunction was still present in 9.9% of patients at three month after surgery. The risk factors for POCD include advanced age,preexisting cognitive impairment,alcohol abuse,and so on. However, according to a vast literature on the subject, these factors are not sufficient to totality clarify the etiology of all cases. In this review article, we briefly assess the factors involved in this cognitive dysfunction .
关键词
术后认知功能障碍
老年人
相关因素
ostoperative cognitive dysfunction
noncardiac surgery
Elderly patients