摘要
非甾体类抗炎药(NSAID)抑制前列腺素的合成,可以减轻炎症和疼痛,在眼科临床有较广泛的适应证。但由于其副作用,使其全身应用受到了一定限制,而眼局部用药在眼科疾病中得到了广泛的应用,尤其是近几年在眼部新生血管的治疗方面取得了较大进展。目前眼科临床上局部应用的NSAID主要有0.1%双氯芬酸钠滴眼液、0.5%及0.4%酮咯酸氨丁三醇滴眼液、0.03%氟比洛芬钠及1.0%苏洛芬钠。此外,还有0.1%吲哚美辛和0.09%溴芬酸等。由于NSAID在某些方面比糖皮质激素更具优势,因此本文就NSAID在眼科的局部应用进行综述,希望能引起临床医生的重视。
Nonsteroidal anti-inflammatory drugs（NSAID）has broad indication in clinical ophthalmology. It has the ability to inhibit the endogenous PGs synthesis, helps to relieve inflammatory reaction and pain. Topical application has less adverse effects than systemic application, and has the advantage in safety and etiicency. Therefore, the topical application of NSAID has been applied comprehensively in ophthalmic diseases. Because NSAID is superior than steroid in some aspects, we aim to take a review on topical application of NSAID in ophthalmology, and hope to cause attention of clinical doctors.
出处
《临床眼科杂志》
2009年第3期284-287,共4页
Journal of Clinical Ophthalmology
作者简介
通讯作者：王雨生（Email：wangys@fmmu．edu．cn）
