摘要
目的:应用光学相干断层成像术(optical coherence tomography,OCT)测量我国正常人黄斑中央小凹厚度,黄斑中心凹体积。方法:用OCT对50例100眼正常人(18～40岁)进行经黄斑中央小凹快速黄斑厚度扫描,扫描深度2mm,采用OCT3000视网膜厚度容量列表分析软件计算黄斑中央小凹厚度、黄斑中心凹体积的均数和标准差。对正常人双眼黄斑中央小凹厚度的均数和标准差进行比较;对正常人双眼黄斑中央小凹体积的均数和标准差进行比较;随机取右眼数值做正常对照组,根据公式x-±1.96s计算出正常人黄斑中央小凹厚度,黄斑中心凹体积的正常参考值。结果:正常人中心小凹厚度为114.54～166.74μm,双眼之间比较差异无统计学意义(P=0.401);正常人黄斑中心凹体积为0.114～0.162mm3,双眼之间比较差异无统计学意义(P=0.153)。结论:OCT能精确测量正常人黄斑视网膜厚度,可为临床黄斑疾病的诊治提供客观、定量的指标。
AIM： To explore the application of optical coherence tomography （OCT） in the measurement of foveola thickness and fovea centralis volume of health adults in our country.
METHODS： Fifty health adults 100 eyes（18-40 years old） were performed fast macular lutea thickness scanning through foveola,and scanning depth was 2mm. The mean and standard deviation of thickness of foveola and volume of fovea centralis were calculated with OCT3000 capacity list of retinal thickness analysis software and compared respectively. Numeruses of right eyes were randomly taken as control group, and normal reference values of thickness of foveola and volume of fovea centralis of health adults were calculated according to the formula x ± 1.96s.
RESULTS： The normal thickness of foveola varied from 114. 54μm to 166. 74μm, and there was no significant difference between two eyes（ P = 0. 401 ） ;The normal fovea centralis volume varied from 0. 114mm^3 to 0. 162mm^3, and there was no significant difference between two eyes too（ P= 0. 153）.
CONCLUSION： OCT seems to be very precision in the measurement of macula retinae thickness in health adults,and can provide objective and quantitative indexs.
出处
《国际眼科杂志》
CAS
2009年第6期1165-1166,共2页
International Eye Science
关键词
光学相干断层成像
视网膜厚度
黄斑
optical coherence tomography
retina thickness
macula lutea
作者简介
通讯作者：仲路，毕业于南京医科大学，主治医师，研究方向：青光眼、斜视。happyz1128@hotmai．com
