摘要
循环肿瘤细胞富集为肿瘤的分期诊断、判断复发、分析预后和制定个体化治疗的有力向导。本文综述了免疫磁珠法富集肿瘤细胞的原理,肿瘤细胞检测的方法比较及常用的细胞表面标志物和目前临床上的实际应用方面的进展。
The enrichment of circulating tumor cells could be a powerful guide for staging diagnosis, judging recurrence, analyzing prognosis and formulating individualized therapy. In this review, we summarized the principle of enrichment of circulating tumor ceils by immunomagnetic beads, comparisons between methods of detecting circulating tumor cells, cell surface bio-markers frequently used and advancements in clinical practical applications of recent years.
出处
《复旦学报(医学版)》
CAS
CSCD
北大核心
2009年第3期369-371,共3页
Fudan University Journal of Medical Sciences
关键词
免疫磁珠法
循环肿瘤细胞
微转移
immunomagnetic beads
circulating tumor cells
micrometastase
作者简介
Corresponding author E-mail:hongguang_701@shmu. edu. cn