摘要
目的:观察中西医结合疗法对高血压晨峰现象控制的效果并进行评价。方法:2006年9月—2007年8月选取本院住院期间具晨峰现象的高血压患者85例,随机分为治疗组和对照组,对照组患者每天晨起口服氨氯地平(络活喜)片剂5mg,苯那普利(洛汀新)片剂10mg;治疗组在此基础上加用杞菊地黄口服液每次10mL,1日3次,共治疗2月。结果:治疗2月后,治疗组、对照组醒后2h血压(SBP)较治疗前下降,有统计学差异(P<0.05),治疗组的晨峰血压SBP较治疗前下降,差异有统计学意义(P<0.05);对照组的有效率为80.9%,治疗组的有效率为95.3%,治疗组的有效率比对照组高,差异有统计学意义(P<0.05)。结论:中西医结合疗法在控制高血压晨峰方面疗效优于单纯西医疗法,中医抗高血压晨峰的具体机制尚待进一步研究。
Objective：To observe and evaluate the regulation effect of the treatment of integrated traditional Chinese and western medicine on decreasing morning blood pressure surge（MBPS）. Methods： conforming eighty inpatients with MBPS were randomized to control group and treatment group. Patients received arrdodipine （5mg/d） and benazepril （10mg/d） in control group for two weeks. While Patients received amlodipine（5mg/d） ,benazepril（10mg/d） and QiJu DiHuang oral liquid （60mL/d） for two weeks. Before and after treatment patients were measured by 24 hour ambulatory blood pressure monitoring （ABPM）. Results ： Comparing to two months ago the significant decrease of average SBP of 2 hours both before and after awake was observed in two groups （ P 〈 0.05 ）. The significant decrease of MBPS＇SBP was observed in treatment group （ P 〈 0.05 ）. A higher effective rate was observed in treatment group（ 95.3% ） than in control group（80.9% ）. Conclusion：A better efficiency for decreasing MBPS was observed in treatment group than in control group.
出处
《中华中医药学刊》
CAS
2009年第5期1110-1112,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
晨峰现象
高血压
中西医结合
morning blood pressure surge
hypertension
integrated traditional and western medicine
作者简介
方伟（1970-），女，浙江宁波人，副主任医师，学士，研究方向：中西医结合治疗的心血管疾病。
