摘要
目的分析综合治疗晚期非小细胞肺癌的临床疗效,总结临床经验。方法根据肿瘤综合治疗的特点,应用SQLsever数据库技术设计晚期非小细胞肺癌病例分析数据库进行统计分析。结果102例患者中位生存期为11.5个月,1年生存率为37.5%。治疗后卡氏评分较前增加,体重稳定,神疲乏力、少气懒言、咳嗽、痰多、疼痛、纳谷少馨、痰中带血、大便干结、便溏等症候改善与治疗前比较,具有非常显著性差异(P<0.01),可有效改善食欲、精神、疲乏、疼痛、自身对癌症的认识、对治疗的态度等。CD4与治疗前相比,具有显著性差异(P<0.05);CD4/CD8,NK细胞活性与治疗前相比,具有非常显著性差异(P<0.01)。结论利用数据库对辨证分型、治则治法进行了分析,并采用加权法计算高频药对来总结临床经验。
Objective To analyze the effect of on comprehensive therapy advanced non - small cell lung cancer, and summarize the clinical experience. Methods Based on the comprehensive therapy characteristic, we designed a clinic cases analysis database using the SQL sever database technique. Results In the 102 patients with advanced non - small cell lung cancer in the Xiyuan Hospital, the mean survival period was 11.5 months and the 1 year survival rate was 37.5% . The weight was stable and KPS was increased. There was significant difference in the improvement of mental weariness and hypodynamia, deficient breath and indolence, cough, abundant sputum, pain, anorexia, sputum mixed with blood, constipation, abdominal diarrhea and distention （P 〈 0.01 ）. The appetite, energy, fatigue, pain, the cognition of his cancer, and the attitude about therapy could be improved in effect. The immune index such as CD4, CD4/CD8 and NK could be improved remarkably. Conclusion We analyzed syndrome differentiation and treatment and summarized the clinical experience of high frequency chinese drug pair with weighted analysis method using database.
出处
《医学研究杂志》
2009年第5期107-111,共5页
Journal of Medical Research
关键词
非小细胞肺癌
数据库
病例分析
Non -small cell lung cancer
Database
Clinical case analysis
