摘要
目的了解下呼吸道感染金黄色葡萄球菌（SAU）的临床科室分布及耐药特征，为临床合理用药提供参考依据。方法对武汉大学人民医院2007年1—12月下呼吸道标本中分离的SAU进行回顾性分析。结果94株SAu中耐甲氧西林金黄色葡萄球菌（MRSA）69株，占73．40％；MRSA对青霉素G100．0％耐药；对万古霉素和替考拉宁100．0％敏感；对氯霉素耐药率为7．24％；对喹诺酮类、大环内酯类、氨基糖苷类抗菌药物耐药率均较高（56．52％～98．55％），且存在多药耐药；MRSA耐药率普遍高于MSSA。结论建议各级医院加强监控力度，预防MRSA医院感染暴发流行。
OBJECTIVE To investigate the distribution and characteristics of drug-resistance of Staphylococcus aureus （SAU） causing lower respiratory infection, for rational using of antibiotics in clinical practice. METHODS A retrospective analysis on S. aureus isolates and their drug-resistance characteristics were carried out. These strains were isolated from lower respiratory specimens in clinical laboratory of Renmin Hospital of Wuhan University from Jan 2007 to Dec 2007. RESULTS Among 94 strains, 69 were meticillin-resistant S. aureus（MRSA）, accounting for 73.40%. All MRSA strains were resistant to penicillin G, while sensitive to vancomycin and teicoplanin. Resistant rate to chloramphenicol was 7.24 %. The average resistance rate of MRSA to quinolones, macrolides and aminoglycosides were relatively high （56.52-98.55%）. And resistant rate of MRSA was higher than the meticillin-sensitive S. aureus （MSSA） in average level. CONCLUSIONS Hospitals at all levels are proposed to strengthen drug resistance supervising so as to prevent the infection breaks.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第8期1008-1010,共3页
Chinese Journal of Nosocomiology
