摘要
作者对50例桥本氏甲状腺炎(HT)和50例Graves病(GD)作了临床及形态学方面的对比观察。按Sato氏分类标准把HT分为单纯型HT和HT伴甲亢;依淋巴细胞浸润等的不同,将单纯型HT、HT伴甲亢和有明显淋巴细胞浸润的GD分为PO、+、++、+++、++++。结果表明GD年龄最轻,单纯型HT最大,HT伴甲亢介于两者之间。从GD到单纯型HT淋巴细胞浸润、滤泡萎缩和纤维组织增生程度逐渐加重,间质血管量减少。提示GD、HT伴甲亢和单纯型HT可能为同一病因作用下而出现的不同临床病理过程,GD为疾病早期,单纯型HT为晚期,HT伴甲亢则为由GD向单纯型HT发展的过渡状态。
Fifty cases of Hashimoto's thyroiditis(HT)were compared with 50 cases of Graves' diease on clinical and morphological characteristics. HT was classified into two groups: simple HT(SHT)and HT with hypothyroidism(HTH). Basing on the degrees of lymphocytic infiltration, follicular atrophy and fibrosis and the number of interstitial blood vesscls, the authors classified SHT, HTH and GD with apparently lymphocytic infiltration into five levels: 0, +, ++, +++ and ++++. It was found that GD patients were the youngest, SHT oldest, HTH between GD and SHT. From GD to SHT, the degrees of lymphocytic infiltration, follicular atrophY and fibrosis aggravated and the number of interstitial blood vessels reduced gradually. The results suggest that GD, HTH and SHT might be variant clinical and pathological processes under the same cause, i. e. GD is the earlier stage, SHT later stage, HTH the stage developing from GD into SHT.
出处
《滨州医学院学报》
1990年第4期66-68,70+95-96,共6页
Journal of Binzhou Medical University
