摘要
应用免疫学检测方法观察了小鼠铝(Al)中毒后对免疫功能的影响及螺旋藻对Al中毒小鼠免疫功能的保护作用。结果表明,灌服氯化铝(每天303.3mg/ kg)20d后,小鼠腹腔巨噬细胞吞噬功能及T、B淋巴细胞转化率均明显降低;而灌服螺旋藻(每天2.0g/kg)20d后,明显改善小鼠Al中毒腹腔巨噬细胞吞噬功能及T、B淋巴细胞转化率。结果提示,螺旋藻对Al中毒小鼠免疫功能的损伤有明显的保护和改善作用。
We observed by immunoassay the effect of aluminium-poison on the immune function in mice and the improvement of spirulina on the immune function in alu-miniun-poisoned mice. The results showed that in the group irrigated by aluminium chloride orally 303.3 mg/(kg. d) for 20 days, the phagcytosis of macrophages and the lymphocytes transformation rate decreased remarkably while in the group irrigated by spirulina orally 2.0 g/(kg. d) for 20 days , the lymphocytes transformation increased evidently. The experimental results indicated that spirulina could protect or improve the immune function of the aluminium-poisoned mice.
关键词
螺旋藻
氯化铝
免疫功能
spirulina
aluminium chloride
immune function