摘要
目的:评估白内障术后疏水性丙烯酸人工晶状体Sensar AR40e和硅胶人工晶状体的后囊膜混浊(PCO),并用能客观评估PCO的软件量化分析。方法:共选择98眼行标准的超声乳化白内障吸除术,人工晶状体囊袋内固定。所有眼随机植入Sensar AR40e或硅胶人工晶状体,但同一患者植入的人工晶状体必须不同。在第1～2a时后照法拍摄后囊膜图像,通过去除浦肯野反光、增强对比度、过滤后增强低密度的PCO等方法处理后用POCO软件分析对比。结果:术后1a疏水性丙烯酸人工晶状体PCO百分比为0.32±0.13,硅胶人工晶状体为0.39±0.17(P=0.37)。2a时疏水性丙烯酸人工晶状体PCO百分比为0.42±0.20,硅胶晶状体为0.34±0.18(P=0.50)。患者术后1,2a时疏水性丙烯酸人工晶状体PCO的严重级别分别是0.50±0.30和0.82±0.58,与硅胶人工晶状体的0.63±0.35和0.55±0.35相比,无统计学意义(P=0.52,P=0.69)。结论:POCO后囊膜混浊量化分析系统提供了客观而且可重复性强的量化PCO的方法,也是研究预防PCO技术的有力工具。
AIM： To evaluate posterior capsular opacification （PCO） with hydrophobic acrylic intraocular lens （IOL, Sensar AR40e） and silicone IOLs after cataract surgery, to use a software program developed to provide an objective assessment of the amount of PCO in the digital images of the posterior capsule to quantify PCO.
METHODS： Ninety-eight eyes underwent standardized phacoemulsification and ＂ in the bag＂ IOL placement, were randomized to receive a three piece lens of hydrophobic acrylic or silicone, but lens materials were different in one case. In year 1 and 2, digitized retro- illumination images were taken from the posterior capsule. Images were analyzed by POCO software program, removing the Purkinje light reflexes, contrast enhancement, filtering to enhance low-density PCO.
RESULTS： The percentage of PCO were 0.32 ± 0.13 of hydrophobic acrylic IOLs in year 1, compared with 0.39 ± 0.17 of silicone （P= 0.37）. In year 2, the percentage of PCO were 0.42 ± 0.20 with hydrophobic acrylic IOLs and 0. 34 ± 0.18 with silicone IOLs （ P= 0.50）. Of those patients with PCO in year 1 and 2, severity grades were 0, 50 ± 0.30 and 0.82 ± 0.58 of hydrophobic acrylic cases, compared with 0.63 ± 0.35 and 0.55 ± 0.35 of patients with silicone IOLs （ P= 0.52, P= 0.69） with no statistical significance.
CONCLUSION： The POCO system is capable of producing an objective and repeatable measure of PCO that is relevant to assessing techniques of PCO prevention.
出处
《国际眼科杂志》
CAS
2009年第3期405-408,共4页
International Eye Science
关键词
后囊膜混浊
量化
丙烯酸
人工晶状体
posterior capsular opacification
quantification
acrylate
intraocular lens
作者简介
丁衍，男，主治陕师，讲师，研究方向：白内障。
通讯作者：柳林，教授，博士生导师，全国眼免疫学组组员、上海眼科学会委员、角膜学组副组长，研究方向：白内障，眼底病．lin—liu@sh163．net
