摘要
目的探讨血液透析滤过(HDF)和间歇性血液透析(IHD)治疗老年慢性肾功能衰竭的疗效、透析相关并发症发生率及对患者营养状况的影响。方法将45例老年慢性肾功能衰竭患者随机分为治疗组(HDF组)23例,对照组(IHD组)22例,检测两组患者治疗前后血清尿素氮(Bun)、肌酐(Scr)、血红蛋白、血清白蛋白;观察皮脂肌肉消耗情况及胸腹水发生率;计算尿素氮清除率(kt/V);并对比两组病人并发症的发生情况。结果治疗组病人kt/V>1.2,对照组病人kt/V<1.2,两组透析充分性比较有统计学意义(P<0.05)。治疗组病人的血红蛋白、血清白蛋白水平显著高于对照组病人;治疗组病人皮脂肌肉消耗不明显;治疗组胸腹水发生率明显低于对照组(P<0.05)。结论血液透析滤过能显著提高患者生活质量,为老年肾功能衰竭患者提供了一个更安全、更高效的治疗模式。
Objective To investigate the therapeutic effect of hemndiafiltration （HDF） and intermittent hernodialysis（IHD）on senile patients with chronic renal failure, the incidence of dislysis correlative syndrome, and the effect on the nutritional status. Methods Forty-five eases were divided in to two groups： 23 eases with hemodiafiltration therapy （group HDF）, and 22 patients treated with intemaittent hemodialysis （group IHD）. The levels of urea nitrogen （Bun） , serum ereatinine （Scr）, hemoglobin and serum albumin were detected; the loss of sebum cutaneum and skeletal muscle, the incidence of pleural fluid and hydroperitoneum were observed; the values of urea nitrogen clearance （kt/V） were calculated; and the incidence of complication in each group was compared in all cases before and after treatment. Results kt/V 〉 12 in HDF group while kt/V 〈 12 in IHD group. The differences of dialysis adequacy between the two groups were significant （P 〈 0.05）. The levels of hemoglobin and serum albumin in HDF group were significantly higher than those in group IHD. There was no obvious loss of scbum cutaneum and skeletal muscle in group HDF. There was low incidence of pleural fluid and ascites in group FIDF. Conclusion hernodiafihration can obviously improve the quality of life of patients , and it is a better way for treating chronic renal failure.
出处
《中国临床新医学》
2008年第B12期45-47,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
作者简介
伍秋霞（1967-），女，大学本科、学士，副主任医师，研究方向：肾内科。E—mail：gbbjkwqx@163．com
