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瘦素及瘦素抵抗与肥胖、2型糖尿病的关系研究进展 被引量:12

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摘要 瘦素是由肥胖(ob)基因编码、脂肪组织分泌的蛋白质类激素。生理作用主要表现在对脂肪及体重的调控,在啮齿类ob基因突变导致肥胖,而人类肥胖可能主要与瘦素抵抗有关。血清瘦素还与胰岛素水平有关,在2型糖尿病的发病中具有潜在作用。本文就对瘦素的主要生理功能及人体内瘦素抵抗现象与肥胖、2型糖尿病的关系方面的研究作一简要综述。
出处 《安徽医药》 CAS 2009年第1期1-3,共3页 Anhui Medical and Pharmaceutical Journal
基金 安徽省"十一五"科技攻关项目(初发2型糖尿病患者亚临床血管病变的中药干预研究)(No:08010302184)
作者简介 通讯作者:方朝晖,男,教授,硕士生导师,研究方向:中医药防治代谢内分泌疾病,E-mail:fangzhaohui@medmail.com.cn
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二级参考文献1

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