摘要
角膜内皮移植是一种新的治疗角膜内皮病变的手术方法，主要是采用健康的角膜内皮片替代病变内皮层。该方法因为几乎不改变患者的角膜曲率和屈光状态，损伤小，视力恢复快，近年来在临床上逐渐被推广应用，取得较好愈后效果。该方法是角膜移植手术不断精细化和向屈光性手术转化的具体体现。角膜内皮移植术后良好的屈光效果和可能的低排斥率，使其有望成为角膜内皮病变治疗的重要方式。但是，目前内皮移植手术仍然需要完善，改进植入方法以减少脱片率和内皮细胞损失率，利用飞秒激光等进一步提高屈光效果，以及观察术后免疫排斥率是今后眼科学者的研究重点。
Endothelial keratoplasty （EK） is a new surgical method in treatment of corneal endothelial keratopathy, which retains healthy portions of a patient＇s cornea while replacing diseased endothelium with healthy donor tissue. In the past decade EK has been used increasingly and has shown better results over standard penetrating keratoplasty. The emergence and improvement of EK demonstrate the convert of corneal transplantation to refined and refractive surgery. EK, which has favorable refractive outcomes and potential low rejection rate, opens a new era for the treatment of endothelial dysfunction. However, there are still some aspects requiring to be studied, such as the methods of implantation to decrease graft dislocation rate and endothelial cell loss, use of femtosecond laser in EK to improve refractive errors, and the long-term result of immune rejection rate.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2008年第12期1144-1148,共5页
Chinese Journal of Ophthalmology
关键词
角膜移植
内皮
角膜
角膜疾病
Corneal transplantation
Endothelium,corneal
Corneal diseases
作者简介
通讯作者：李绍伟，Email：shaoweili2005@yahoo．com.cn
