摘要
目的:探讨脑梗死后发生痴呆的相关因素。方法:300例脑梗死急性期住院患者分为痴呆组(45例)和非痴呆组(255例)。于住院期间及脑卒中3个月后利用MMSE及ADL等量表进行神经心理测试,分析脑梗死后痴呆的相关因素。结果:脑梗死后痴呆的发生率为15%。痴呆组的平均年龄比非痴呆组明显偏高,差异有统计学意义。在低教育程度、糖尿病、脑卒中史、饮酒等方面,痴呆组的发病率明显高于非痴呆组,差异有统计学意义。结论:脑梗死后痴呆是退行性因素和血管性因素共同作用的结果。年龄、低教育水平、糖尿病、脑卒中史和饮酒与脑梗死后痴呆的发生相关。
Objective： To examine relative factors for dementia after ischemic stroke. Methods： A total of 300 consecutive patients with ischemic stroke were enrolled in this study, and 300 patients were examined with MMSE, ADL, etc during admission and 3 months after stroke to screen out one＇s who had cognitive impairment, and then assessed with a battery of neuropsycholgical tests. The group of dementia was 45 and undementia group was 255. t test and χ^2 test were used to evaluate the incidence and to find the relative factors for dementia after ischemic stroke. Results： The study indicated the incidence of dementia after ischemic stroke was 15%. The patients with dementia after ischemic stroke more often had old age. low educaltional level, diabetes mellitus （OR = 6. 719, P =0. 025）, alcohol drinking history （OR = 23. 500, P =0. 000） and stroke history （OR = 5. 833, P =0. 040） were relative with dementia after ischemic stroke with stastically significance. Conclusion： Stroke increases the risk of dementia. Vascular factors play a master role in the pathogenesis of dementia after ischemic stroke. Relative factors for dementia after ischemic stroke are age, low educational level, diabetes mellitus, alcohol drinking and stroke history.
出处
《新疆医科大学学报》
CAS
2008年第11期1567-1568,1570,共3页
Journal of Xinjiang Medical University
关键词
脑梗死
痴呆
相关因素
dementia
ischemic stroke
relative factors
作者简介
周国栋（1965-），男，主治医师，本科，研究方向：脑血管病。
