摘要
目的:探讨糖尿病患者血小板参数、血液流变学和凝血功能指标的临床价值。方法:对46例糖尿病有微血管病变患者、46例糖尿病无微血管病变患者和90例正常对照组的血浆凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原进行检测,测定三组人群血流变参数及血小板参数。结果:糖尿病有微血管病变组凝血酶原时间、活化部分凝血活酶时间、凝血酶时间均低于糖尿病无微血管病变组,而纤维蛋白原高于糖尿病无微血管病变组,两者之间差异有统计学意义(P<0.05);血小板参数中平均血小板体积高于糖尿病无微血管病变组(P<0.05),而血小板分布宽度、血小板计数和血小板压积差异均无统计学意义(P>0.05);血流变参数中全血黏度、血浆黏度、红细胞压积均高于糖尿病无微血管病变组。结论:常规检测血小板参数、血液流变学和凝血功能指标,对糖尿病微血管病变患者的病情预测和早期诊治有重要意义。
Objective To explore the clinical significance of the platelet, hemorheology and coagulation parameters in patients with diabetes mellitus. Methods The levels of PT, APTT and TT, FIB, the platelet parameters and hemorheology in 46 diabetes mellitus patients with microangiopathy amt 46 diabetes mellitus of PT, APTT and TT in in the group of diabetes viscosity were obviously patients with the group of without mic higher than out mlcroanglo diabetes with pathy and 90 normal controls. Results The levels microangiopathy were obviously lower than those roangiopathy. But those in the group FIB, MPV, Hct, whole blood an of diabetes without microangiopat d plasma hy （P〈0. 05）. There were statistic differences in PDW, Conclusion Determination of the four platelet and important clinical value to the early prevention and PLT and PCT between two groups （P 〉0. 05）. hemorheology and coagulation parameters has an treatment of diabetes with microangiopathy.
出处
《中华实用诊断与治疗杂志》
2008年第11期801-803,共3页
Journal of Chinese Practical Diagnosis and Therapy
关键词
糖尿病
凝血功能
血小板参数
血液流变学
Diabetes mellitus
coagulation
platelet parameters
hemorheology
作者简介
李德奎（1972年-），男，主管技师，本科，研究方向：临床检验基础。
