摘要
模拟高原梭曼中毒大鼠脑单胺递质含量变化刘勇吕宏宇欧阳子倩赵清（第三军医大学预防医学系毒理学教研室，重庆６３００３８）梭曼是一种难防难治的有机磷神经性毒剂，由于中枢及周围神经系统的胆碱酯酶活性被抑制而导致乙酰胆碱蓄积，进而诱发一系列胆碱能神经亢奋的症状...
The contents of monoamines in rat brains were measured to investigate the effects of soman poisoning at a simulated altitude of 4000 meters. The results showed that the contents of monoamines, including 5 HT, 5 HIAA, NE and DA, were increased after the animals entered the highland and the effects were further exaggerated by acute soman poisoning. The hypoxia may play an important role in the changes in monoamines in rat brains due to soman exposure at altitude.
出处
《中国药理学与毒理学杂志》
CAS
CSCD
北大核心
1997年第4期302-303,共2页
Chinese Journal of Pharmacology and Toxicology
关键词
梭曼中毒
毒剂毒理
脑
单胺递质
altitude
poisoning, soman
monoamine transmitters
brain
