摘要
目的探讨血浆纤维蛋白原含量变化与冠状动脉病变严重程度的关系。方法选择AMI患者20例（AMI组），48小时内劳力型心绞痛加剧和出现自发性心绞痛患者24例（UAP），典型心绞痛发作，其性质在1～3个月内无法改变的SAP患者18例（SAP组）．健康对照20例，采用美国库尔特公司的ACL-9000全自动血凝分析仪，测定其血浆，进行比较分析。结果AMI组和UAP组患者的血浆纤维蛋白原含量均高于SAP组和健康对照组（P〈0.05）。但AMI组与UAP组患者之间血浆纤维蛋白原含量无显著性差异（P〉0．05）。结论血浆纤维蛋白原含量与冠状动脉病变严重程度相关，急性冠状动脉综合征时体内处于高凝状态，抗凝和溶栓治疗有助于降低冠状动脉实践的危险性。
Purpose Explore the relation between the change of plasma fibrinogen content and the serious extent of coronary artery pathology. Method Choose 20AMI patients （AMI team）, the 24 who aggravates Labor type angina pectoris and appears spontaneity angina pectoris is UAP（ UAP team）, 18 SAP patients, who flares up typical angina pectoris, and the character can not change in 1 ~ 3 months is SAP team. （ SAP team）, and 20 healthy person for contrast. Adopt American Kurt company＇s ACL-90OO Full-automatic blood curdles analytical Instrument, test their plasma, compare and analyze. Result Those who are in AMI team and UAP team patients＇ plasma fibrinogen content are hither than the SAP teams＇ and Health contrast teams （ P 〈 0.05 ）. But there is no remarkable difference between AMI team and UAP teams＇ （ P 〉 0. 05 ） . Conclusion Plasma fibrinogen content is interrelated to the serious extent of coronary artery pathology, when in a cute coronary artery syndrome, the body is in high agglutinate, anti-clotting and dissolving thrombus treatment is useful to lower the dangerous of coronary artery practice.
出处
《世界科技研究与发展》
CSCD
2008年第5期645-646,共2页
World Sci-Tech R&D
