光聚合法快速制备甲基丙烯酸酯类毛细管整体柱被引量：4

Rapid Preparation of Methacrylate Capillary Monolithic Columns by Photopolymerization

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摘要采用甲基丙烯酸正丁酯(BMA)为功能单体,乙二醇二甲基丙烯酸酯(EDMA)为交联剂,正丙醇、1,4-丁二醇和水为致孔剂,Irgacure 1800为引发剂,在毛细管内采用光引发原位聚合150 s快速制备了有机聚合物整体柱.分别采用电色谱(CEC)、加压电色谱(p-CEC)和低压色谱(LPLC)模式对所制备的整体柱进行了性能评价,基线分离了硫脲、甲苯、萘和联苯,在加压电色谱(p-CEC)模式下硫脲的最低理论塔板高度达到了8.0μm.扫描电镜结果表明,整体材料在毛细管柱中形成并与毛细管内壁结合紧密. An organic-based monolithic column was quickly prepared inside the fused-silica capillary, and in situ photopolymerization was carried out in 150 s, using butyl-methacrylate（BMA） as a functional monomer, ethylene glycol dimethacrylate （EDMA） as a cross-linking agent, 1-propanol, 1,4-butanediol and water as porogenic solvents and Irgacure 1800 as an initiator. The electrophoretic and chromatographic behavior was comparatively evaluated using pressure-assisted CEC （p-CEC）, CEC and low pressure-assisted liquid chromatography modes（LPLC）. Baseline separation of the model analytes was respectively achieved including thiourea, toluene, naphthalene and biphenyl with the lowest theoretical height up to 8.0 μm for thiourea in the mode of p-CEC. A scanning electron micrograph of a cross-section of the capillary column shows that the monolithic columms were formed in the center of the capillary and adhered to the column inner wall.

作者陈娜张裕平张毅军叶雄文屈凌波袁倬斌

机构地区郑州大学化学系河南科技学院中国科学院研究生院化学化工学院

出处《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2008年第10期1969-1972,共4页 Chemical Journal of Chinese Universities

基金中韩国际合作项目(批准号:20611140646) 河南省高校新世纪优秀人才(批准号:2006HNCET-01) 高校骨干教师项目资助

关键词光聚合整体柱加压电色谱甲基丙烯酸酯 Photopolymerization Monolithic column Pressure-assisted electrochromatography Methacrylate

分类号 O657 [理学—分析化学]

作者简介联系人简介：张裕平，博士，教授，主要从事色谱方法学应用研究．E-mail：beijing2008zyp@163．com

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