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病理学与基因 被引量:1

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摘要 当前病理学工作者们正不断将现代科学研究的新进展和新技术应用于病理学领域,以探寻疾病发生的分子机制,建立诊断方法和技术,为防治疾病提供科学的理论基础与实用工具。解剖学、组织学以及免疫学等并行学科的发展也促进了病理学的发展。在现代细胞和分子生物学高速发展的今大,以基因为研究对象,以规模化生物技术为支撑的生命科学新学科——基因组学也必将丰富病理学的研究内容和手段,为病理学带来革命性的改变。
作者 张猛 于军
出处 《中华病理学杂志》 CAS CSCD 北大核心 2008年第10期649-650,共2页 Chinese Journal of Pathology
作者简介 通信作者:于军(E-mail:junyu@big.ac.cn)
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参考文献7

  • 1Watson JD, Crick FH. Molecular structure of nucleic acids, a structure for deoxyribose nucleic acid. Nature, 1953,171 (4356) : 737-738.
  • 2Lander ES, Linton LM, Birren B, et al. Initial sequencing and analysis of the human genome. Nature, 2001,409 ( 6822 ) : 860- 921.
  • 3International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature, 2004, 431 (7011) :931-945.
  • 4Margulies M, Egholm M, Altman WE, et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature,2005,437 (7057) :376-380.
  • 5International HapMap Consortium. A haplotype map of the human genome. Nature ,2005,437 (7063) : 1299-1320.
  • 6Levy S, Sutton G, Ng PC,et al. The diploid genome sequence of an individual human. PLoS Biol,2007,5(10) :e254.
  • 7van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature, 2002, 415(6871 ) :530-536.

同被引文献16

  • 1汪世容,关柏林.转化医学:B2B医疗新模式.文汇报,2008-11-08(7).
  • 2Vanden Bempt I, Van Loo P, Drijkoningen M, et al. Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing. J Clin Oncol, 2008, 26(30) :4869-4874.
  • 3Swerdlow SH, Campo E, Harris NL, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press, 2008 : 233-237.
  • 4Feder JN, Gnirke A, Thomas W, et al. A novel MHC class 1-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet, 1996, 13(4):399-408.
  • 5Debiec-Rychter M, Sciot R, Le Cesne A, et al. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer, 2006, 42 ( 8 ) : 1093-1103.
  • 6Cobo M, Isla D, Massuti B, et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase Ⅲ trial in non-small-cell lung cancer. J Clin Oncol, 2007, 25(19):2747-2754.
  • 7Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med, 2006, 355(10) :983-991.
  • 8Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature, 2008, 455 (7216) : 1061-1068.
  • 9陈杰,霍临明.与时俱进,不断丰富病理学科的内涵[J].中华病理学杂志,2008,37(2):73-74. 被引量:1
  • 10吕亚莉,钟梅,刘琳,韦立新,赵坡.乳腺癌17号染色体多体的临床病理意义[J].中华病理学杂志,2008,37(2):88-91. 被引量:6

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