摘要
Bioactive and bioresorbable composite materials were fabricated from poly-L-lactide and bioactive glass (average particle size 6.8 μm) by a solvent evaporation technique.Cellular cultivation in vitro and MTT assay were conducted for evaluating the influence on morphology,growth and proliferation of cultured fibroblasts.The results of cytotoxicity testing show that cells cultured in extracts of PLLA/BG and on the surface of composites demonstrate normal growth and proliferation.The bioactive glass in PLLA composite facilitates both adhesion and proliferation of rat fibroblasts on PLLA/bioactive glass composite film.
Bioactive and bioresorbable composite materials were fabricated from poly-L-lactide and bioactive glass （average particle size 6.8 μm） by a solvent evaporation technique. Cellular cultivation in vitro and MTT assay were conducted for evaluating the influence on morphology, growth and proliferation of cultured fibroblasts. The results of cytotoxicity testing show that cells cultured in extracts of PLLA/BG and on the surface of composites demonstrate normal growth and proliferation. The bioactive glass in PLLA composite facilitates both adhesion and proliferation of rat fibroblasts on PLLA/bioactive glass composite film.
出处
《中国有色金属学会会刊：英文版》
EI
CSCD
2008年第5期1151-1156,共6页
Transactions of Nonferrous Metals Society of China
基金
Project(50771096) supported by the National Natural Science Foundation of China
关键词
生物活性玻璃
复合材料
生物相容性
化学反应
poly-L-lactide
bioactive glass
composite
cytotoxicity
biocompatibility
in vitro
作者简介
Corresponding author： RUAN Jian-ming; Tel： ＋86-731-8876644; E-mail： jianming@mail.csu.edu.cn
