摘要
目的观察复方苦参注射液联合顺铂腹腔灌注治疗卵巢癌腹水的疗效。方法确诊为卵巢癌腹水的患者共46例,两组均静脉给于泰素150mg/m2,随机分成两组:A组,复方苦参注射液20ml和顺铂100mg联合腹腔灌注用药组26例,B组单纯顺铂组20例。两组患者在腹腔穿刺抽液后,分别注入不同药物,比较两种处理方法对腹水消失有无差别。结果腹灌6次后,两组患者腹水消失或减少有差别(P<0.05),A组优于B组。结论复方苦参注射液、顺铂联合用药对消除卵巢癌腹水有促进作用,值得进一步推广。
Objective To evaluate the effects of compound kushen injection plus cisplatin on ascites caused by ovarian carcinoma throuth transperitoneal perfusion. Methods A total of 42 eases who had been diagnosed as having malignant ascites caused by ovarian carcinoma were randomly assigned to receive compound kushen injection plus cisplatin （group A, n = 26 ） or cisplatin alone（ groups B, n = 20） by transpefitoneal perfusion every two weeks. All of the 42 cases were administered paclitaxel 150mg/m^2 every 21 days. After 6 times of perfusion, the efficacy in ascites was compared. Results There were significant differences between the two groups in efficacy of ascites（ P 〈 0.05 ）, with group A showing better improvement than in group B. Conclusion Compound kushen injection plus cisplatin can enhance the reduction of the amount of ascites caused by ovarian carcinoma,which may be made more widespread.
出处
《四川医学》
CAS
2008年第9期1153-1154,共2页
Sichuan Medical Journal
关键词
复方苦参注射液
顺铂
腹腔灌注
卵巢癌
腹水
compound kushen injection
cisplatin
transperitoneal perfusion
ovarian carcinoma
ascites
