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冷冻联合外用干扰素治疗男性尖锐湿疣的疗效观察

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摘要 目的评价冷冻联合外用干扰素治疗男性尖锐湿疣的治愈率和复发率。方法将80例患者随机分为2组进行比较,冷冻组病人仅作液氮冷冻治疗;冷冻加干扰素组在液氮冷冻治疗的同时联合外用干扰素凝胶治疗。结果冷冻组治愈率为67.5%,复发率达32.5%;而冷冻加干扰素组治愈率为87.5%,复发率仅为12.5%,两组之间有显著性差异。结论冷冻加干扰素组的治愈率高于冷冻组,且复发率低于冷冻组。故冷冻联合外用干扰素是治疗尖锐湿疣的较好方法之一。
出处 《皮肤病与性病》 2008年第3期47-48,共2页 Dermatology and Venereology
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参考文献3

  • 1Holman DM, Kalaaji AN. Cytokines in dermatology [ J]. J Drags Dermatol,2006,5 (6) :520 - 524.
  • 2应作霖,吴瑞勤.尖锐湿疣患者的免疫功能和免疫治疗研究进展[J].皮肤病与性病,2006,28(3):12-15. 被引量:17
  • 3Gross G, Rogozinski T, Schofer H, et al. Recombinant interferon beta gel as an adjuvant in the treatment of recurrent genital warts: results of a placebo- controlled double-blind study in 120 patients [J]. Dermatology, 1998,196(3) :330-334.

二级参考文献18

  • 1李中伟,于长平,李娜,侯建玲,郑荣涛,周盛基.尖锐湿疣患者IL-2、sIL-2R、IFN-γ和IFN-α水平的检测[J].中国麻风皮肤病杂志,2004,20(5):427-429. 被引量:19
  • 2钱起丰.尖锐湿疣患者血清白介素10水平及其与白介素2关系的研究[J].中华皮肤科杂志,1996,29(3):172-174. 被引量:41
  • 3Cauda R,Tyring SK,Grossi CE,et al.Patients with condyloma acuminatum exhibit decreased interleukin-2 and interferon gamma production and depressed natural killer activiky[J].J C1 in lmmunol,1987,7 (4):304-309.
  • 4Galea LJ,Darling D,Gan SU,et al.Expression of a variant of CD28 On a subpopulation of human NK cells:implications for B7-mediated stimulation of NK cells[J].J Immunol,1999,163 (1):62-70.
  • 5Zingoni A,Palmieri C,Morrone S,et al.CD69-triggered ERK activation and functions are negatively regulated by CD94/NKG2-A inhibitory receptor[J].Eur.J Immunol,2000,30 (2):644-651.
  • 6Morelli AE,Belardi G.Dipaola G.et al.Cellular subsets and epitheliaI ICAM-1 and HLA-DR expression in human papillomavirus infection of the vulva[J].Acta Derm Venereol,1994,74(1):45 -50.
  • 7Coleman N,Birley HD,Renton AN,et al.Immunological events in regressing genital warts[J].Am J Clin Pathol,1994,102(6):768 -774.
  • 8Huang GT,Zhang X,Park NH.Increased ICAM-1 expression in transformed human oral epithelial cells:molecular mechanism and functional role in peripheral blood mononuclear cell adhesion and lymphokine-activated-killer cell cytotoxicity[J].Int J Oncol,2000,17 (3):479-486.
  • 9Hurd DS,Conte ET.Practical uses of the interferon in dermatology[J].Int J Dermatol 1998,37 (12):881-896.
  • 10Stanley MA.Imiquimod and the imidazoquinolones:mechanism of action and therapeutic potential[J].Clin Exp Dermatol,2002,27 (7):571-577.

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