摘要
目的探讨胎粪吸入综合征(MAS)与婴幼儿喘息的关系。方法对2003年1月至2007年1月在我院住院的64例MAS患儿随访1年,观察其喘息的发病情况、特应性体质的表现及生后家庭成员是否有吸烟者,同时进行食物过敏原、吸入过敏原筛查及肺炎支原体抗体(MP-IgM)检测,并与对照组比较,分析MAS与早期婴幼儿喘息的相关性。结果MAS患儿婴幼儿喘息的发生率为25.0%,显著高于对照组7.5%(P<0.01);重度MAS婴幼儿喘息的发生率显著高于轻度MAS(P<0.05);两组中有特应性体质的比较差异无统计学意义(P>0.05);生后家庭成员中有吸烟者比较差异无统计学意义(P>0.05);两组发生喘息的患儿中食物过敏原、吸入性过敏原筛查阳性率及MP-IgM阳性率比较差异均无统计学意义(P>0.05)。结论早期婴幼儿喘息的发病与MAS密切相关,并与其轻重程度有关;MAS疾病本身可能导致喘息,建议有针对性地进行早期干预。
Objective To investigate the relationship （MAS） and wheezing in infants. Methods All 64 infants with year. The prevalence rate of wheezing physical characteristics between meconium aspiration syndrome MAS were followed-up for a period of 1 and smoking history in the family were observed. The mycoplasma pneumonia antibodies （MP-IgM）, food allergy and inhaled allergens were investigated in wheezing children. Results The incidence of wheezing in infants with MAS （25.0%） were significantly higher than the that in the controls （7.5%） （P 〈0. 01 ） ; The wheezing incidence in infants with severe MAS were significantly higher than those with mild MAS （ P 〈 0. 05 ）. There was no difference in appearance oi physical characteristics and smoking history in the family between the study groups and the controls （ P 〉 0. 05 ） ; The positive rate was no difference in MP-IgM, food allergy and inhaled allergens of the wheezing children between the two groups （P 〉 0. 05 ）. Conclusion Wheezing in early infancy is associated with MAS, and its severity MAS itself might be the causative factor of wheezing and early interventional management is recommended.
出处
《中国新生儿科杂志》
CAS
2008年第5期280-282,共3页
Chinese Journal of Neonatology
关键词
胎粪吸入综合征
哮喘
婴儿
Meeonium aspiration syndrome
Asthma
Infant
