摘要
目的观察子宫内膜异位症术后应用异位宁与丹那唑的疗效及副反应。方法选择Ⅲ期子宫内膜异位症术后患者60例，随机分为3组。异位宁组于术后第7天口服异位宁2次／d，200ml／次；丹那唑组于术后第7天口服，2～3次／d，200mg／次，疗程均为6个月，随访6～30个月。对照组术后两种药均不用。结果异位宁、丹那唑组复发率分别为4．0％和4．5％低于未用药纽的30．7％（P〈0．05），异位宁与丹那唑纽复发率无显著性差异（P〉0．05），异位宁副反应率8％明显低于丹那唑组22．7％（P〈0．05）。结论异位宁于预防子宫内膜异位症术后复发与丹那唑的疗效相似，但副反应少，易于广泛应用。
Objective To observe the clinical efficacy and side - effects of YiWeiNing and Danazol on treatment of patients with endometriosis （ stage Ⅲ ） after laparotomy. Methods 60 eases of endometriosis （ stage Ⅲ ） after laparotomy were randomly divided into 3 groups： YiWeiNing group was administered YiWeiNing 200ml, Bid, from the 7th day after laparotomy;Danazol group which was administered 200rag of Danazol, Bid - Tid, from the 7th day after laparotomy, for 6 months and was followed up for 6 -30 months ; Control group wasn 〈t administered the two medicines. Results The recurrent rats of YiWeiNing group, Danazol group and control group were 4% , 4.5% and 30.9%. There was not statistic significance between YiWeiNing group and Danazol group （ P 〉 0.05 ）. There was statistic significance between the treatment group and control group （ P 〈 0.05 ）. The side - effect rate of YiWeiNing group and Danazol group were 8% and 22.7%. The differences in the groups had statistic significance. Conclusion YiWeiNing was similar to Danazol in the therapeutic effects to prevent postoperation recurrence, but YiWeiNing has few side -effects and was widely applied in clinical treatment.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2008年第8期2025-2026,共2页
Lishizhen Medicine and Materia Medica Research
作者简介
杨东霞（1977-），女（汉族），黑龙江哈尔滨人，现任黑龙江中医药大学附属第二医院主治医师，博士学位，主要从事中医药治疗子宫内膜异位症及慢性盆腔炎的实验和临床研究工作．
