摘要
目的对比研究系统性红斑狼疮（SLE）患者与慢性疾病（冠心病、糖尿病、高血压）患者的健康相关生存质量（HRQOL）。方法选择门诊的SLE缓解期患者、住院活动期SLE患者及门诊的冠心病、糖尿病、高血压患者进行健康状况调查问卷简表-36（sF-36）量表调查，分析量表各维度得分并进行比较。结果SLE组平均年龄（39±13）岁，冠心病组（65±16）岁，糖尿病组（60±13）岁，高血压组（59±14）岁。SLE组患者年龄明显小于其他慢性疾病组（P〈0．05）。缓解期SLE患者的sF-36量表各维度得分与其他慢性疾病没有差别，而活动期的SLE患者各维度与慢性病及缓解期SLE比较差异均有统计学意义（P〈0．05）。结论活动期SLE患者比其他慢性病患者的生存质量明显下降。
Objective To compare the Health Related Quality of Life （HRQOL） of patients with systemic lupus erythematosus （SLE） with other common chronic diseases （coronary heart disease, diabetes and hypertension）. Methods Responses from Short Form-36 （SF-36） questionnaires from outpatients, inpatients with SLE, other common chronic diseases and healthy controls were analyzed in all domains. Results The mean age of patients with SLE was 39±13 years old, while those of patients with coronary heart disease, diabetes and hypertension were 65±16, 60±13, 59±14 years respectively. All SLE patients were significantly worse in all domains of SF-36 questionnaire, compared with the healthy controls. The responses of inactive patients with SLE, were not significantly worse than those with other chronic diseases in all domains （P〉0.05）. On the contrary, the responses of patients with active SLE were significantly worse than those of patients with inactive SLE, as well as patients with other chronic diseases （P〈0.05）. Conclusion HRQOL of patients with active SLE is significantly worse when compared to patients with other common chronic diseases.
出处
《中华风湿病学杂志》
CAS
CSCD
2008年第8期543-545,共3页
Chinese Journal of Rheumatology
关键词
红斑狼疮
系统性
慢性病
健康状况指标
Lupus erythematosus, systemic： Chronic isease
Health status indicators
作者简介
通讯作者：张志毅，Email：zhangzhiyi@medmail．com.cn
