摘要
目的讨论CA125测定在肺结核、结核性胸膜炎与肺癌鉴别诊断中的价值。方法对27例菌阳肺结核、21例结核性胸膜炎及18例肺癌患者的血清CA125进行检测,同时检测其他11项肿瘤标记物的血清浓度(如CEA、CA199、CA242等),对以上3组的检测结果进行分析。结果结核性胸膜炎组血CA125浓度(75.43±28.74KU/L)高于肺癌组(42.09±16.41KU/L)及肺结核组(23.26±7.59KU/L),统计学有显著性差异(P<0.05)。肺癌组CA125高于肺结核组,两组比较有显著性差异(P<0.05)。其他肿瘤标记物阳性率:肺癌组(38.9%)高于肺结核组(3.7%)和结核性胸膜炎组(4.76%),差异有显著性(P<0.05)。结论血CA125检测在肺结核及肺癌鉴别诊断中有重要的临床价值,结合肿瘤标记物其他项目的检测结果及动态观察CA125浓度的变化更有利于明确诊断。
Objective To study the value of serum CA125 on the diagnosis of pulmonary tuberculosis、tuberculous pleurisy and lung cancer.Method This study included 66 subjects who were divided into 3 groups.Group of pulmonary tuberculosis consisted of 27 pulmonary tuberculosis patients with positive sputum,while measurement of serum CA125 and other 11 tumor markers（Such as CEA,CA199,CA242,etc）.Group of tuberculous pleurisy consisted of 21 patients with tuberculous pleurisy.Group of lung cancer consisted of 18 patients with lung cancer.The levels of tumor markers were measured.Result The serum CA125 concentration in group of tuberculous pleurisy（75.43±28.74 KU/L） was higher than group of lung cancer （42.09±16.41 KU/L） and pulmonary tuberculosis（23.26±7.59 KU/L）（P〈0.05）.CA125 levels in group of lung cancer was higher than group of pulmonary tuberculosis（P〈0.05）.The positive rate of the other tumor markers in the group of lung cancer（38.9%） was higher than group of pulmonary tuberculosis （3.7%） and group of tuberculous pleurisy（4.76%） （P〈0.05）.Conclusion The measurement of serum CA125 level is beneficial in the determination of pulmonary tuberculosis.
出处
《临床肺科杂志》
2008年第9期1160-1161,共2页
Journal of Clinical Pulmonary Medicine
关键词
CA125
肺结核
肿癌
Serum CA125 determination
Pulmonary tuberculosis
Lung cancer
