摘要
目的:分析在我院ICU重症颅脑外伤患者肺部感染的菌群分布、发生率等因素,探讨防范与治疗措施。方法:对ICU 126例重症颅脑患者进行医院感染调查,计算肺部感染的发病率并进行菌群分析。结果:出现肺部感染29例,感染率为23.0%。由患者痰标本经细菌学检验分离出致病菌37株,阳性例数较多的为革兰阴性菌,其敏感的抗菌药物为亚胺培南/西司他丁、头孢呱酮/舒巴坦、阿米卡星;对耐亚胺培南/西司他丁革兰阳性球菌对万古霉素、复方新诺明敏感;真菌感染对氟康唑耐药增多,对斯皮仁诺仍敏感。结论:本组病例肺部感染有多重耐药、多重感染的特点,故应合理先用抗菌药物,建立严格的保护性隔离措施,积极治疗脑外伤促进早日清醒。
Objective： Investigating flora distribution and incidience of serious craniocerebral trauma cases accompanying pulmonary infection in ICU to formulate preventive and therapeutic use. Methods： we studied hospital infection in 126 cases of serious craniocerebral trauma to count flora distribution and pulmonary infection incidience. Results： 29 cases occurred pulmonary infection in our study. The incidence rate was 23.0%. In the clinical sputum , 37 bacteria strains were isolated, The Gram-positive bacilli were more than the Gram-negative bacilli . The effective antibiotics included imipenem/cilastatin sodium, cefopera-zone/sulbactam, amikacin, et al. Vancomycin and SMZ-TPM were also effective to the resistance-imipenem/cilastatin sodium Gram-positive bacilli . Fungal infection was more resistant to fluconazole, but was sensitive to itraconazole. Conclusions： There are multi-drug resistance and multi-infection in the cases of our study. So we must use antibiotics properly, establish the strict protection and treat brain trauma properly for the recovery.
出处
《河北医学》
CAS
2008年第9期1067-1069,共3页
Hebei Medicine
关键词
肺部感染
颅脑外伤
ICU
Pulmonary infection
Craniocerebral trauma
Intensive care unit
