摘要
目的探讨不同瞳孔直径下，调节对年轻正视眼单色高阶波阵面像差的影响。方法干预性试验研究设计。使用光线追踪原理的波阵面像差仪测量12只年轻正视眼自然生理状态，在4．0,3．0、2．0mm瞳孔直径下，0．00、1．00、2．00、3．00和4．00D调节刺激下的单色波阵面像差。采用单因素方差分析及最小显著差法多重比较，对获得的数据进行统计学分析。结果调节松弛下正视眼的总高阶像差、总彗差、总高阶散光、总球差和总三叶草像差的均方根值均随瞳孔直径减小而减小。在4．0、3．0、2．0mm瞳孔直径下，总彗差是调节松弛状态总高阶像差的最主要成分；总高阶像差仅在调节刺激达4．00D时升高（P〈0．05）。瞳孔直径4．0mm时，随调节刺激增加，4阶球差出现从大到小、从正值向负值的变化，但在瞳孔直径为3．0和2．0mm时，4阶球差始终为正值。3阶水平方向三叶草像差在4．0、3．0、2．0mm瞳孔直径下均表现出从负值向正值变化的规律。结论不同瞳孔直径不同调节刺激下，正视眼各项单色高阶波阵面像差发生了不同规律和方向的变化。高阶像差在调节过程变化的意义和对不同注视距离视觉处理过程的作用有待于进一步研究，波阵面像差的研究将从单纯的消除向优化方向发展。
Objective To study the effect of accommodation on monochromatic higher-order aberrations in different pupil sizes in the young emmetropes. Methods Intervention trial design was used in the study. The monochromatic aberrations were measured in 12 eyes from 12 undulated young emmetropes in 4.0 mm, 3.0 mm, and 2. 0 mm pupil sizes with a ray tracing wavefront aberrometer under accommodative stimuli from 0 to 4.00 D. Results RMS values of total high-order aberrations （ HOAs）, total coma, total higher-order astigmatism, total spherical, and total trefoil aberrations significantly decreased as pupil size decreased in the relax state. In 4.0 mm, 3.0 ram, and 2.0 mm pupil sizes, the average root mean square （RMS） value of total coma was the highest item of HOAs in the relaxed state. With accommodation up to 3.00 D, the RMS of HOAs remained constant but changed significantly at 4. 00 D stimulation （P 〈 0.05 ） in all these three pupil sizes. The 4th spherical aberration decreased and changed from positive to negative with increasing accommodation over 4.0 mm size, whereas it remained positive under all accommodative levels over the 3.0 mm and 2.0 mm zones, and no trend was found. The 3rd order trefoil 0 changed from negative to positive with increasing accommodation, with 4. 0 mm, 3.0 mm, and 2. 0 mm pupil sizes. Conclusions In 4. 0 mm, 3.0 mm, and 2. 0 mm pupil sizes, under accommodative stimuli from 0. 00 to 4. 00 D, dramatical trends amongst the HOAs, spherical, coma, and trefoil aberrations were demonstrated. Most of the higher-order aberrations induced by accommodation deserves further investigation. Simple elimination of the higher-order aberrations will be replaced by the optimization of aberrations.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2008年第7期603-608,共6页
Chinese Journal of Ophthalmology
基金
广东省科技计划基金资助项目（2005830901006）
关键词
眼
瞳孔
调节
眼
像差
Eye
Pupil
Accommodation,ocular
Aberrations
作者简介
（吴文捷为博士研究生，现在福建省立医院眼科）
通讯作者：张振平，Email：zhenpinz@hotmail．com
