摘要
目的探讨原发性肾病综合征(PNS)患者血清甲状腺激素的变化规律、临床意义,以及应用甲状腺素片治疗后的效果。方法采用放免法测定60例PNS患者的甲状腺素水平,与60例正常对照组的甲状腺素水平比较,并观察在常规治疗基础上加用左旋甲状腺素的治疗效果。结果PNS患者约87%甲状腺素水平有不同程度降低,治疗后有所回升,且左甲状腺素治疗组缓解率明显高于对照组。结论PNS患者合并甲状腺功能减退患者在常规治疗基础上给予小剂量左甲状腺素,不仅有利于甲状腺功能恢复,且有利于病情缓解。
Objective To investigate the level of FT3 FT4 TT3 TT4 and TSH in PNS and Euthyrox efficacy in treatment of the disease. Methods Radioimmunoassay（RIA） was used to determine the level of TT3 , TT4 , FT3 , FT4 ,TSH in 60 patients before and after the routine treatment , the patients with poor response to the routine treatment were give Euthyrox on the basis of routine therapy. Results The levels of TT3 ,TT4, FT3, FT4 and TSH were decreased in various degrees in PNS, after the treatment, the above parameters were increased, In the treatment with Euthyrox, the increase in the parameters were greater than in the patients with the routine treatment （ P 〈 0.05 ）. Conclusion On the top of the routine treatment, a low-dosage of Euthyrox was not only beneficial to the recovery of throid function, but also to disappearance of urinary protein.
出处
《中国现代药物应用》
2008年第14期24-25,共2页
Chinese Journal of Modern Drug Application
