摘要
目的:优选复方天麻滴丸最佳成型工艺。方法:针对影响滴丸制备因素考察料温、基质种类、滴距、药物与基质配比等影响因素,并以丸重相对标准偏差、圆整度为测评指标,最终确定最佳成型工艺条件。结果:药物与基质的配比为3∶7,料温:80℃,滴距:1 cm,基质种类PEG4000∶PEG6000=1∶1;该成型工艺可靠,重现性良好。结论:采用均匀设计法优选复方天麻滴丸的成型工艺可行。
Objective： To select the best froming techniques for Compound Tall Gastrodia Tuber drop pills. Methods：According to the factors that affect the quality of drop pill, we selected four factors as temperature of drop solution, the variety of matrix, the ratio be- tween drug and matrix, the dropping distance, and then we selected the RSD of weight of dripping pills and the roundness as index ex- amination. Results ： The optimum techniques as follows ： the ratio between drug and matrix was 3 ： 7, the temperature of drug solution was 80~C, the dropping distance was 1 cm, the composition of matrix was PEG4000：PEG6000 = 1： 1. The method adopted was steady and feasible. Conclusion：It＇s feasible to seek the optimum techniques making Compound Tall Gastrodia Tuber drop pills by uniform design method.
出处
《中药材》
CAS
CSCD
北大核心
2008年第6期902-904,共3页
Journal of Chinese Medicinal Materials
基金
贵州省中医药管理局基金支助项目(200306)
关键词
复方天麻滴丸
均匀设计
成型工艺
Compound Tall Gastrodia Tuber drop pills
Uniform design method
Forming techniques
作者简介
李江（1973-），男，副教授，博士，从事中药复方及苗药研究；Tel：0851-5937181，E-mail：lijiang2005zy@126．com.
