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冠状动脉药物支架再狭窄形式分析 被引量:1

Coronary restenosis morphology after intracoronary drug eluting stents implantation
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摘要 目的:分析冠状动脉支架置入后造影复查的影像资料,寻找不同药物支架再狭窄的特点。方法:收集冠状动脉介入治疗后造影复查再狭窄患者121例,共159处病变,进行再狭窄形式分析。结果:裸支架(BMS)和药物支架(DES)后再狭窄病变局限性再狭窄分别占39.80%和70.49%(P<0.001);弥漫性再狭窄病变分别占60.20%和29.51%(P<0.001);三种不同类型DES(Cypher,Taxus和Firebird)再狭窄形式没有差异,局限性再狭窄分别为83.33%,55.56%和75.00%(P=0.070);弥漫性再狭窄分别占16.67%,44.44%和25.00%,(P=0.070)。结论:①DES改变了以往BMS再狭窄模式,由弥漫型转为局限型;②不同种类的药物支架再狭窄形式没有差异。 Objectives:To evaluate the morphology of in-stent restenosis after different kinds of stents. Methods: 121 Patients with 159 restenosis lesions after intracoronary interventional therapy were included in this study. Restenosis morphology of different kinds of stents were analysed. Results: The focal restenosis in drug eluting stent (DES) and bare metal stent (BMS) was 39.80% and 70.49% respectively (P = 0. 000) ; Diffuse restenosis was 60.20% and 29.51% (P 〈 0.001 ). The morphology of the different kinds of DES ( Cypher, Taxus and Firebird) was similar ( focal restenosis was 83. 33% , 55. 56% and 75.00%, P = 0.070 ; diffuse restenosis was 16.67 %, 44.44% and 25.00% , P = 0.070). Conclusion: DES changed the morphology of in-stent restenosis, from diffuse restenosis to focal restenosis ; Different DES has the similar morphology of restenosis.
出处 《军医进修学院学报》 CAS 北大核心 2008年第3期231-232,共2页 Academic Journal of Pla Postgraduate Medical School
关键词 血管成形术 经腔 经皮 冠状动脉 支架 冠状动脉再狭窄 percutaneous intraluminal angioplasty stent restenosis
作者简介 金琴花,女,黑龙江省海林市人,1995年北京医科大学临床专业毕业,2005年军医进修学院心血管内科博士毕业,主治医师。E-mail:jinqinhua@sohu.com
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参考文献3

  • 1Mehran R,Dangas G,Abizaid AS,et al.Angiographic patterns of in-stent restenosis:classification and implications for long-term outcome[J].Circulation,1999,100:1872-1878.
  • 2Lemos PA,Saia F,Ligthart JMR,et al.Coronary restenosis after sirolimus-eluting stent implantation[J].Circulation,2003,108:257-260.
  • 3Colombo A,Orlic D,Stankovic G,et al.Preliminary observations regarding angiographic pattern of restenosis after rapamycin-eluting stent implantation[J].Circulation,2003,107:2178-2180.

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