摘要
目的观察参芪扶正注射液联合吉西他滨加顺铂方案治疗晚期非小细胞肺癌的疗效和毒副反应。方法治疗组35例，对照组35例，均采用相同的吉西他滨加顺铂（GP）化疗方案，即吉西他滨（健泽）1g／m^2第1、8天，顺铂25mg／m^2第1～3天。治疗组加用参芪扶正注射液（丽珠集团利民制药厂生产）250mL静脉滴注，1次／d，连用10d。结果两组疗效差异无显著性（P〉0．05）；治疗组血液毒性反应和消化道反应发生率明显低于对照组，差异有显著性（P〈0．05）。结论参芪扶正注射液联合GP方案治疗晚期非小细胞肺癌可降低化疗对患者的毒副反应，改善患者的生活质量。
Objertive To observe the efficary and toxicity of Shenqi Fuzheng injection combined with GP regimen to treat patients with advanced non-small cell lung cancer （NSCLC）. Methods Gemcitabin 1g/m^2 iv gtt D1,8 and DDP 25mg/m^2 iv gtt D1 -3 ;combined with Shenqi Fuzheng injection 250ml Qd for 10 days in the treated group. Results Difference between the two groups on therapeutic effect showed no significance（ P 〉 0. 05 ） ;The hematological toxicity and gastrointestinal reactions in the treated group were lower than those in the control group with combined significant difference （ P 〈 0. 05 ）. Conclusion When used to treat patients with advanced NSCLC Shenqi Fuzheng injection combined with GP regimen were more effective and with lower toxicities.
出处
《医学综述》
2008年第12期F0002-F0002,F0003,共2页
Medical Recapitulate
关键词
非小细胞肺癌
参芪扶正注射液
药物疗法
Non-small cell lung cancer
Shenqi Fuzheng injection
Drug treatment
