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心力衰竭患者社区获得性肺炎病原学分布及耐药性分析 被引量:9

Pathogen Distribution of Community-Acquired Pneumonia in Heart-failure Patients and Analysis of the Related Drug-resistance
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摘要 目的探讨心力衰竭患者社区获得性肺炎(CAP)病原学分布,为临床合理使用抗菌药物治疗提供理论依据。方法选取77例心力衰竭并社区获得性肺炎患者,采用病原学检查、显微镜鉴定、细菌培养等方法,对病原菌构成及耐药性进行分析。结果共检出病原菌98株,以革兰阴性细菌为主,前5位病原菌分别为铜绿假单胞菌(18.4%),假丝酵母菌(17.3%),肺炎克雷伯菌(13.2%),鲍曼不动杆菌(10.2%);单纯感染占83.1%,混合感染占16.9%。大多数病原菌存在多重耐药性。结论心力衰竭并CAP患者以革兰阴性细菌为主,目前已呈现多重耐药性,应引起临床高度重视。 Objective To investigate the pathogen's distribution of community-acquired pneumonia (CAP) in heart-failure patients for the clinical treatment guidance using antibacterial drug therapy. Methods 77 CAP patients with heart-failure were recruited for the analysis of pathogenic bacteria compositionand drug resistance by pathogenic detection, microscopic identification, and bacterial culture. Results 98 pathogenic bacteria were identified in all patients. Most of them were Gram negative. Top five pathogens are bacteria as Pseudomonas aeruginosa (18.4%), fungi(17.3%), Klebsiella pneumonia (13.2%), Escherfchfa coli (12.2 %), Acinetobacter haumannii (10. 2 %). The infection rate was 83.1% in simple infection and 16.9% in polyinfection cases. Multidrug resistantance was observed for majority of pathogenic bacteria. Conclusion The most common pathogenic bacteria is Gram negative bacteria with multidrug resistantance in CAP patients with heart-failure.
出处 《福建医科大学学报》 2008年第3期271-273,共3页 Journal of Fujian Medical University
关键词 心力衰竭 充血性 社区获得性感染肺炎 抗菌性 细菌 微生物敏感性试验 heart failure congestive community-acquired infections pneumonia drug-resistance, bacterial microbial sensitivity tests
作者简介 徐训发(1974-),男,主治医师,医学硕士
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