摘要
方法观察不同剂量的银杏达莫注射液对中型颅脑损伤患者血清中神经元特异性烯醇化酶（NSE）含量变化的影响，初步探讨银杏达莫注射液治疗颅脑损伤的治疗机理。方法应用酶联免疫检测法检测33例颅脑损伤患者血清中NSE含量，并分析其结果。结果颅脑损伤患者的NSE水平明显高于空白对照组（P〈0．05），银杏达莫注射液可降低颅脑损伤患者NSE含量，并呈剂量依赖性，中、高剂量组降低更为明显。结论银杏达莫注射液可降低颅脑损伤患者血清中NSE含量可能是其治疗机理之一。
Objective To observe the effects of different doses of Yinxingdamo injection on changes of nerve-specific enolase （NSE） of patients with medium-sized brain injury and discusse the mechanism of Yinxingdamo injection in the treatment of brain injury. Methods The contents of serum NSE in 33 cases of craniocerebral injury were dectected by ELISA test and the results were analyzed. Results NSE levels in patients with brain injury were significantly higher than normal people （p 〈0.05）. Yinxingdamo injection can reduce the content of NSE for brain injury patients. This reduction related with the dosage of the medicine, showing the higher the dosage is used, the greater reduction may be. Conclusion Yinxingdamo injection can reduce NSE in serum of patients with brain injury, and this may be the mechanism of Yinxingdamo injection in treating craniocerebral injury.
出处
《国际中医中药杂志》
2008年第3期201-201,204,共2页
International Journal of Traditional Chinese Medicine
